Perioperative Use of Ketamine

Patients’ perioperative experiences of an opioid-free versus opioid-based care pathway for laparoscopic bariatric surgery: A qualitative study

“…A meta-analysis of Hung et al (2022) exploring the impact of opioid-free anaesthesia on bariatric surgery reported psychomimetic adverse events described as hallucinations in two out of eight trials for which ketamine was used in their anaesthetic regimen. However, ketamine has not been observed to negatively impact patient safety and remains a valuable approach for perioperative pain control, particularly in individuals with high body mass index who are at high risk of opioid-related adverse effects, such as postoperative respiratory depression ( Adegbola et al, 2023 ; Olausson et al, 2021 ). While esketamine and ketamine are related compounds, esketamine is associated with fewer psychomimetic adverse events ( Xie et al, 2023 ) than ketamine.…”

Attenuation of intestinal ischemia-reperfusion-injury by anesthetics: a potentially protective effect of anesthetic management in experimental studies

“…Ketamine is often used for anesthesia, analgesia, and sedation, but its applications beyond anesthesia are involved in the treatment of addiction, depressive episodes, asthma, and even inhibit cancer growth ( Ivan Ezquerra-Romano et al, 2018 ; Nowacka and Borczyk, 2019 ; Mihaljević et al, 2020 ; Ritter et al, 2020 ; Adegbola et al, 2023 ). In addition, ketamine can also protect various tissues from IRI ( Xiao et al, 2012 ; Li et al, 2018 ).…”