Perioperative use of 0.12% chlorhexidine gluconate for the prevention of alveolar osteitis

Hermesch, Charles B; Hilton, Thomas J.; Biesbrock, Aaron R; Baker, Robert A.; Cain-Hamlin, Janet; McClanahan, Stephen F.; Gerlach, Robert W

doi:10.1016/s1079-2104(98)90061-0

Cited by 108 publications

(53 citation statements)

References 32 publications

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“…CHX is an antiseptic often applied in the form of mouthwash and bioadhesive gel in clinical practice. Studies showed that using 0.12% CHX mouthwash perioperatively could decrease the incidence of AO in mandibular third molar surgical extraction(s) significantly (Field et al , ; Hermesch et al , ; Caso et al , ; Daly et al , ), and some reports have encouraged the use of CHX to rinse extraction sockets (Bonine, ; Shepherd, ). However, its action is rapid but not prolonged.…”

Section: Introductionmentioning

confidence: 99%

The efficacy of intra‐alveolar 0.2% chlorhexidine gel on alveolar osteitis: a meta‐analysis

Zhou

Liu

et al. 2016

Oral Diseases

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Section: Introductionmentioning

confidence: 99%

The efficacy of intra‐alveolar 0.2% chlorhexidine gel on alveolar osteitis: a meta‐analysis

Zhou

Liu

et al. 2016

Oral Diseases

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“…Amler, studied 11 biopsy specimens from the alveoli of the patients diagnosed as dry socket, taken in intervals from third day through ninth day postoperatively and concluded that alveolar osteitis appears as a result of healing disruption between clot formation and granulation tissue formation [9].…”

Section: Introductionmentioning

confidence: 99%

The Efficacy of 1% Chlorhexidine Gel on the Reduction of Dry Socket Occurence Following Surgical Third Molar Extraction— Pilot Study

Ahmedi¹,

Ahmedi²,

Agani³

et al. 2014

OJST

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Aim & Objectives: The aim of this prospective pilot-study was to assess the efficacy of intra alveolar application of 1% chlorhexidine gel (CHX) on the reduction of dry socket (DS) occurrence following surgical extraction of mandibular third molars. Materials and Methods: A randomized split-mouth-design study included twenty-five patients with bilaterally impacted lower third molars (partial or full bone) requiring full thickness mucoperiastal flap reflection for extraction. Following surgical extraction of third lower molar, 2 ml of gel containing 1% chlorhexidine digluconate (Chlorhexamed ® Gel 1%) were placed in the experimental side, and saline solution was used for irrigation in the control side of extraction sockets, both followed by suturing of extraction site. The surgeries and follow up examinations were performed by the same surgeon. The follow up visits were performed at 48 hours and on day seven, post surgery where presence or absence of dry socket using the Blum criteria for diagnosis was evaluated and pain intensity by Visual Analogue Scale (VAS) 0 -100 was observed. Results: In this pilot study, dry socket was present in 4.0 and 28.0% of cases in the experimental and control groups, respectively (P = 0.048). Fisher's test revealed a statistically significant reduction of dry socket occurrence following the use of 1% CHX gel versus saline solution. Conclusion: The application of CHX gel 1% may significantly reduce the incidence of DS following third molar extraction. Prophylactic use of CHX gel 1% may be suggested in all patients, especially in the patients at risk of development of DS. KeywordsDry Socket; Chlorhexidine 1%; Third Molar Surgery J. Ahmedi et al. 153

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“…Chlorhexidine is a chemical antiseptic used to combat microbes and intraorally, it is used as 0.1, 0.12, and 0.2 % [3][4][5][6] with favorable suture cleansing, healing and epithilialisation of tissues [3,5]. It is both bacteriocidal and bacteriostatic.…”

Section: Introductionmentioning

confidence: 99%

A Prospective Clinical Evaluation of the Effects of Chlorhexidine, Warm Saline Mouth Washes and Microbial Growth on Intraoral Sutures

Fomete

Saheeb

Obiadazie

2014

J. Maxillofac. Oral Surg.

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Introduction Post operative care of sutured wound is important after surgery. Sutured wounds within the oral cavity are kept clean through frequent rinses with either normal saline, chlorhexidine mouth rinses, hydrogen peroxide diluted with saline, or fresh tap water. Patients and Methods The patients were randomised into 3 groups (A, B and C). The container used had 34 chlorhexidine, 34 warm saline and 32 warm water mouth rinses. The latter served as control. All selected patients had scaling and polishing done preoperatively when needed. All participants in each group did not receive antibiotics but received analgesics (paracetamol 1 g 8 h for 5 days,). Results There were 49 females and 51 males, in the age range between 18 and 50 years. Microorganisms were found to grow on sutures with streptococcus viridians predominating followed by staphylococcus epidermides. The effects of chlorhexidine, warm saline and warm tap water mouth washes were not statistically significant. Conclusion Chlorhexidine, warm salt water and warm tap water averagely produced the same number of colony forming units of bacteria, which shows that the three different mouth washes are equally effective as post-operative mouth rinses after oral surgery.

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Perioperative use of 0.12% chlorhexidine gluconate for the prevention of alveolar osteitis

Cited by 108 publications

References 32 publications

The efficacy of intra‐alveolar 0.2% chlorhexidine gel on alveolar osteitis: a meta‐analysis

The efficacy of intra‐alveolar 0.2% chlorhexidine gel on alveolar osteitis: a meta‐analysis

The Efficacy of 1% Chlorhexidine Gel on the Reduction of Dry Socket Occurence Following Surgical Third Molar Extraction— Pilot Study

A Prospective Clinical Evaluation of the Effects of Chlorhexidine, Warm Saline Mouth Washes and Microbial Growth on Intraoral Sutures

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