“…Several studies, however, clearly show that fluid overload leads to poor patient outcome as well. Excessive amounts of intraoperative fluid causes decreased pulmonary function (17), reduced gut motility (3,18), and postoperative complications and increased morbidity in both vascular surgery (19,20), pneumonectomy (21,22), and liver transplantation (23). Furthermore, intraoperative fluid "restriction" predicts shorter length of stay in ICU after, respectively, spine (24) or vascular (25) surgery and in the gastrointestinal surgery restriction or "zero-balance" fluid therapy reduces postoperative complications (2,3,26,27).…”