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2021
DOI: 10.3390/healthcare9030333
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Perioperative Pain Management and Opioid Stewardship: A Practical Guide

Abstract: Surgical procedures are key drivers of pain development and opioid utilization globally. Various organizations have generated guidance on postoperative pain management, enhanced recovery strategies, multimodal analgesic and anesthetic techniques, and postoperative opioid prescribing. Still, comprehensive integration of these recommendations into standard practice at the institutional level remains elusive, and persistent postoperative pain and opioid use pose significant societal burdens. The multitude of guid… Show more

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Cited by 90 publications
(79 citation statements)
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References 504 publications
(852 reference statements)
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“…If not well handled, pain can become chronic within 3 to 4 months, being much more difficult to treat, if at all. In consequence, this leads to impaired quality of life, both from a social and economic point of view, particularly through the chronic consumption of opioids [28].…”
Section: Discussionmentioning
confidence: 99%
“…If not well handled, pain can become chronic within 3 to 4 months, being much more difficult to treat, if at all. In consequence, this leads to impaired quality of life, both from a social and economic point of view, particularly through the chronic consumption of opioids [28].…”
Section: Discussionmentioning
confidence: 99%
“…A pharmacist, regardless of their practice setting, can focus their efforts on medication reconciliation, assessing patient specific factors to guide pain medication selection and optimization, and identifying opportunities for deprescribing and tapering opioids to support opioid stewardship and aid in efforts to improve communication during TOC 41‐43 . Consistent delivery of pain management must be comprehensive and include collaboration with the patient and interprofessional team to establish goals of therapy and a multimodal treatment plan, screening for ORADEs and OUD risk factors prior to the start of opioid therapy, utilizing evidence‐based pain management strategies, implementation of effective patient monitoring and distribution of naloxone.…”
Section: Discussionmentioning
confidence: 99%
“…Moreover, in cases of prolonged ileus, the potential for a protracted exposure to significant doses of lipid-soluble opioids may be associated with the development of opioid tolerance [2]. Concurrently, many postoperative patients may find themselves discharged on large doses of opioids for ongoing analgesia, with a proportion continuing such drug therapy because of poorly managed pain, opioid tolerance or dependence, or simply poor opioid stewardship [3]. The resulting complications are part of the 240% increase in hospitalisations and deaths in Australia related to opioid over-use since 2000 [4].…”
Section: Introductionmentioning
confidence: 99%