Perioperative myocardial ischaemia in patients undergoing surgery for fractured hip randomized to incremental spinal, single-dose spinal or general anaesthesia

Neuraxial anesthesia for orthopedic surgery: systematic review and meta-analysis of randomized clinical trials

“…15 Berggren et al 15 Bigler et al 16 Casati et al 18 Davis et al 22 Davis et al 23 Eroglu et al 25 Hole et al 27 Jones et al 28 Juelsgaard et al 30 McKenzie et al 34 McLaren et al 35 Nielson et al 37 Racle et al 38 Riis et al 39 Valentin et al 41 White et al 42 Williams-Russo et al 43 Random = 0.00; Chi 2 = 14.80, df = 10 (P = 0.14); I 2 = 32% Test for overall effect: Z = 1.15 (P = 0.25) Test for subgroup differences: Chi 2 = 1.29, df = 2 (P = 0.53); I 2 = 0% not possible to pool the data for degree of satisfaction, blood transfusion requirements or quality of life. The data on the degree of satisfaction and blood transfusion requirements were not described correctly in the studies included.…”

“…16,22,23,27,30,34,35,38,41,42,44 Three types of surgery were conducted in the studies included: hip, femur and knee surgery. There were no statistically significant differences between the types of surgeries (RD = -0.01; 95% CI: -0.04 to 0.01; P = 0.25; 1903 participants) (Figure 4).…”

“…Thus, 17 articles with the potential to answer our research question were identified. 15,16,18,22,23,25,27,29,30,34,35,[37][38][39]41,42,44 We also analyzed 441 titles from the reference lists of these 17 studies included, but did not find any additional studies (Figure 1). …”

“…30 The other studies included did not report sufficient details to determine whether they presented high or low risk of bias, or they reported that the outcome assessors were blinded.…”

“…41 In the study by Juelsgaard et al, usable Holter data were obtained from 43 patients out of the 54 participants. 30 Selective reporting. In two of the studies included, the authors reported results relating to outcomes that were not described in the method.…”