Perioperative Management of Patients Undergoing Elective Colorectal Surgery in Israel: A National Survey

Shpitz, Baruch; Reissman, Petachia; Rabau, Michael Y.; Ziv, Yehiel

doi:10.1089/sur.2005.6.305

Cited by 4 publications

(2 citation statements)

References 23 publications

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“…Although traditional triple antibiotic prophylaxis (aminoglycoside, an antianaerobic, and penicillin) is now only used by a small proportion of surgeons in the United States (2), it remains common in other countries (3, 4). …”

Section: Introductionmentioning

confidence: 99%

Cefotetan versus Conventional Triple Antibiotic Prophylaxis in Elective Colorectal Cancer Surgery

et al. 2010

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This study examined infectious outcomes in elective colorectal cancer surgery between cefotetan alone or conventional triple antibiotics. From January to December 2007, 461 consecutive primary colorectal cancer patients underwent elective surgery. Group A contained 225 patients who received conventional triple antibiotics (cephalosporin, aminoglycoside and metronidazole) for prophylaxis, and group B contained 236 patients who received cefotetan alone for prophylaxis. Treatment failure was defined as the presence of postoperative infection including surgical-site infection (SSI), anastomotic leakage, and pneumonia or urinary tract infection. The two groups were similar in terms of demographics, American Society of Anesthesiologists (ASA) score, tumour location, stage, surgical approach (conventional open vs. laparoscopy-assisted), and type of operation. The treatment failure rates were 3.1% in Group A and 3.4% in Group B (absolute difference, -0.3%; 95% confidence interval [CI], 0.39 to 3.07, P=0.866), with SSI being the most common reason for failure in both groups (2.7% in Group A and 3.0% in Group B [absolute difference, -0.3%; 95% CI, 0.37 to 3.37, P=0.846]). Cefotetan alone is as effective as triple antibiotics for prophylaxis in primary colorectal cancer patients undergoing elective surgery.

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Section: Introductionmentioning

confidence: 99%

Cefotetan versus Conventional Triple Antibiotic Prophylaxis in Elective Colorectal Cancer Surgery

et al. 2010

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“…또 다른 연구들에서는 2세대 혹은 3세대 cephalosporin을 단독으로 사용하는 방법 보다 metronidazole과 병용하는 방법이 더 효과적인 것으로 나타났다 6,[7][8][9][10]. 반면 많은 외과의들은 연구 결과 및 권 장 사항을 실제 적용하지 못하고 다른 종류, 다른 용법의 예 방적 항생제를 사용하고 있으며, 일부 외과의들은 3가지 항 생제를 병용하는 3제 병용요법을 사용하기도 한다.…”

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Dual Therapy and Triple Therapy of Prophylactic Antibiotics After Elective Colorectal Surgery: A Comparative Study

Kim

Lee

Ahn

et al. 2009

J Korean Soc Coloproctol

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The use of prophylactic antibiotics is the current standard of care after elective colorectal surgery. The aim of this study was to compare the efficacy of antibiotic prophylaxis with dual antibiotic therapy and triple antibiotic therapy after elective colorectal surgery. Methods: We studied consecutive patients underwent elective colorectal surgery from January to June, 2007. Patients of triple-therapy group were administered second cephalosporin, metronidazole, and aminoglycoside for early 3 mo and dualtherapy group were administered second cephalosporin and metronidazole for next 3 mo. The prophylactic antibiotics were administered 2-3 doses for 24 hr after surgery. The surgery for diverticulitis, inflammatory bowel disease, and colon obstruction were excluded. Wound conditions were checked on alternate days during the hospital stay and follow up at least for 30 days after discharge. Results: Over 6 mo, 110 patients were enrolled (59 dual-therapy group, 51 triple-therapy group). In two group, sex, age, American Society of Anesthesiology score, body mass index, combined diseases, and location of disease were similar. Wound infection rate were 1.7% in dual-therapy group and 2.0% in triple-therapy group (P=1.0). Anastomotic leakage rate were 5.1% in dual-therapy group and 2.0% in triple-therapy group (P=0.622). Conclusion:The addition of aminoglycoside to dual antibiotic therapy, second cephalosporin-metronidazole showed no advantage in prevention of postoperative wound complications. Further studies are required to establish appropriate guideline of antibiotic prophylaxis after elective colorectal surgery.

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Preoperative Bowel Preparation in Gynecologic Oncology

Wells

Plante

McAlpine

2011

International Journal of Gynecological Cancer

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Perioperative Management of Patients Undergoing Elective Colorectal Surgery in Israel: A National Survey

Cited by 4 publications

References 23 publications

Cefotetan versus Conventional Triple Antibiotic Prophylaxis in Elective Colorectal Cancer Surgery

Cefotetan versus Conventional Triple Antibiotic Prophylaxis in Elective Colorectal Cancer Surgery

Dual Therapy and Triple Therapy of Prophylactic Antibiotics After Elective Colorectal Surgery: A Comparative Study

Preoperative Bowel Preparation in Gynecologic Oncology

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