Perioperative management in a case of glucose-6-phosphate dehydrogenase deficiency undergoing orthopaedic surgery

Doshi, Chaula; Tandale, Sushama Raghunath; Mohite, Shubha N; Nagaria, Anisha

doi:10.4103/1658-354x.159485

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2020

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“…3 However, several case reports suggest their safe use during anaesthesia. [4][5][6] In our patient, use of isoflurane did not result in haemolysis. Sharma et al, reported use of total intravenous anaesthesia with propofol, remifentanil and dexmeditomidine.…”

Section: Discussionmentioning

confidence: 93%

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Anaesthesia for a child with glucose-6-phosphate-dehydrogenase deficiency: a case report

et al. 2020

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<p class="abstract">Patients with glucose-6-phosphate-dehydrogenase (G6PD) deficiency are prone to acute haemolytic crisis during perioperative period, precipitated by oxidative stress and certain medications, which are common concurrences during this period. Careful peri-operative planning, judicious use of medication and postoperative monitoring plays a pivotal role in preventing complications in these patients. Here, we report a successful case of general anaesthesia in a child with G6PD deficiency. </p>

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Section: Discussionmentioning

confidence: 93%

“…Blood transfusions may be needed only infrequently. 5 Such episodes usually settle by day 10. 1 In our patient, careful planning and monitoring with avoidance of triggers led to an uncomplicated recovery.…”

Section: Discussionmentioning

confidence: 99%