Perioperative ischemic injury after coronary bypass graft surgery

Li, Wei-i; Hanelin, Laurence G.; Riggins, Robert C.K.; Agnew, Richard C.; Annest, Lon; Anderson, Richard P.

doi:10.1016/0002-9610(85)90020-0

Cited by 7 publications

(3 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…n 'ont pas d#montr# de diff#rence avec ceux qui avaient un TcPPi-SPECT n#gatif (n = 46) quant ~ la fr#quence (inf#rieure ~ !00 bpm), pression art#rielle systolique (100-120 mmHg) ou la pression veineuse centrale (8)(9)(10)(11)(12)(13)(14)(15)(16) It is well known that haemodynamic stability is essential in the anaesthetic management of coronary artery bypass graft (CABG) surgery. A strong correlation between intraoperative tachycardia ~' 2 and myocardial ischaemia I-3 leading to perioperative myocardial infarction (PMI) has been established.…”

Section: Les Buts De Cette Dtude Prospective Dtaient D'#valuer Les Vamentioning

confidence: 99%

Postoperative haemodynamic and pharmacological responses in patients with positive technetium pyrophosphate single-photon emission computed tomography following CABG

et al. 1992

View full text Add to dashboard Cite

show abstract

Section: Les Buts De Cette Dtude Prospective Dtaient D'#valuer Les Vamentioning

confidence: 99%

Postoperative haemodynamic and pharmacological responses in patients with positive technetium pyrophosphate single-photon emission computed tomography following CABG

et al. 1992

View full text Add to dashboard Cite

show abstract

“…Serial creatine phosphokinase isoenzyme (CK mb) concentrations obtained before operation and at well defined intervals during the postoperative period, are frequently used to measure myocardial damage after CABG. A certain amount of enzyme release always occurs following revascularization, probably because of surgical trauma to the heart, ischaemic injury to the cells, washout from previously jeopardized myocardium, lung damage, haemolysis or defibrillation [31,32,42,60,66]. Thus the peak increase in CK mb is of limited value.…”

Section: Diagnosismentioning

confidence: 99%

“…When using all three of these diagnostic tests (ECG, enzymes and scanning) it is commonly concluded that a patient has suffered PMI when at least two tests are positive. One positive test alone, is regarded as a false positive [7,60].…”

Section: Diagnosismentioning

confidence: 99%

Perioperative Myocardial Infarction

Haagensen¹,

Steen²

1988

British Journal of Anaesthesia

View full text Add to dashboard Cite

The risk of developing myocardial infarction (MI) in connection with surgery and anaesthesia has been recognized for at least 75 years [19, 79, 93, 101]. Since then numerous reports have been published, some describing the incidence and characteristics of perioperative myocardial infarction (PMI), others the risk factors involved. To compare these publications is difficult because of the great span in years between various studies, and the variability in study conditions such as selection and size of population, the use of a retrospective or a prospective approach, variations in postoperative care, the method of diagnosis of PMI etc. These factors can at least partly explain the variability and even contradictions observed in results. In most of these studies statistical evaluation also leaves much to be desired. The questions are often multifactorial, without the appropriate tests being performed. Performing simple chi-squared tests on whether sex, age, type or duration of anaesthesia etc, influence the infarction rate, does not provide a correct picture. There is often some co-variation between many of these factors, such as duration of anaesthesia and type of surgery. Thus the papers should be evaluated critically and the effects of a single factor reported in a single paper should be interpreted with caution. Even more impressive, therefore, are the similarities in some of the results in spite of these differences in methodology, and certain trends appear in the literature that are important to the daily work of the anaesthetist. In this review we have concentrated on the epidemiological aspects of PMI and the risk factors that have practical consequences in the treatment of patients. Frontline research concerning the pathophysiology of myocardial ischaemia and infarction and possible effects of

show abstract