Perioperative Gastric Emptying Is Not a Predictor of Early Postoperative Nausea and Vomiting in Patients Undergoing Laparoscopic Cholecystectomy

Abstract

The incidence of postoperative nausea and vomiting is frequent after laparoscopic cholecystectomy. This study has shown that perioperative gastric emptying is not a predictor of early postoperative nausea and vomiting in patients undergoing laparoscopic cholecystectomy.

The effect of anesthetic technique on early postoperative gastric emptying: comparison of propofol-remifentanil and opioid-free sevoflurane anesthesia

“…We have previously shown that the perioperative gastric emptying rate is not a predictor for PONV [14], and gastric decompression during anesthesia does not reduce the incidence of PONV [15].…”

The effect of intravenous dextrose administration for prevention of post-operative nausea and vomiting after laparoscopic cholecystectomy: A double-blind, randomised controlled trial

“…As a common substitute for traditional open cholecystectomy, LC has been introduced in cholelithiasis management; however, the evidence shows excessive episodes of PONV after LC. [ 18 19 ] Many studies have been conducted to evaluate the efficacy of different antiemetic medications in preventing PONV after LC, with a variable success rate. Such medication may also be problematic in terms of side effects including hypotension, dysphoria, excessive sedation, hallucination and dry mouth.…”

“…Although gastric emptying may be delayed by hyperglycaemia, causing gastric fullness and nausea sensation,[ 24 ] it has been demonstrated that perioperative gastric emptying in patients undergoing LC is not a predictor of early PONV. [ 19 ]…”

Náuseas y vómitos postoperatorios

“…El estrés de la cirugía mayor per se estimula el sistema nervioso simpático y puede reducir sustancialmente el flujo sanguíneo esplácnico. La isquemia intestinal desencadena un ascenso importante de 5-HT3 y otros factores eméticos Durante la manipulación intestinal, podría liberarse serotonina de las células enterocromafines de la mucosa, y ésta podría actuar sobre la ZGQ tanto a través de la circulación sistémica como estimulando las vías aferentes de los nervios vago [16].…”

“…No está claro si el uso de sonda orogástrica o nasogástrica para descompresión gástrica, presentación de NVPO, dado que la documentación existente al respecto no es concluyente [16,19].…”