Perioperative corticosteroid use in paediatric neuro-oncology

Pre-operative dosing of dexamethasone for the management of children with posterior fossa tumours: are we getting it right?

“…Based on this advice we suggest using the range shown in table 2 together with the clinical picture. This is broadly in line with new guidelines suggested by Caruthers et al 4 The burden of disease may dictate a higher dose of steroid and may be used at the discretion of the treating clinician; however, the suggested guidance would serve to minimise the harmful effects of large doses in most of the cases that present to local hospitals. A more robust clinical guidance is required which is likely to be achieved through an expert panel.…”