Perioperative Antibiotic Prophylaxis - Still Room for Improvement

Ruef, C.

doi:10.1007/s15010-002-7302-5

Cited by 4 publications

(2 citation statements)

References 4 publications

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“…The available data on the effect of perioperative antibacterial prophylaxis are incomplete, but published studies reveal a high potential for improving the standard workflow [75,76]. As in the therapy for meningeal infection, the eligible antibiotics should act in a bactericidal manner and have the capacity to penetrate the blood-brain barrier in sufficient amounts.…”

Section: Perioperative Antibacterial Prophylaxismentioning

confidence: 99%

Epidemiology, Prevention and Management of Ventriculoperitoneal Shunt Infections in Children

Prusseit

Simon²,

Brelie³

et al. 2009

Pediatr Neurosurg

118

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The advent of ventriculoperitoneal shunts (VPS) represented a substantial progress in the neurosurgical management of hydrocephalus in children. VPS infection is the most frequently observed complication. VPS infection is related to substantial morbidity and mortality, and exerts a negative impact on the quality of life of patients. Considerable personnel and financial resources have been devoted to its diagnosis and treatment. This article reviews the current literature and includes suggestions for the prevention, diagnosis and management of VPS infections.

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Section: Perioperative Antibacterial Prophylaxismentioning

confidence: 99%

Epidemiology, Prevention and Management of Ventriculoperitoneal Shunt Infections in Children

Prusseit

Simon²,

Brelie³

et al. 2009

Pediatr Neurosurg

118

View full text Add to dashboard Cite

show abstract

“…A survey of German hospitals found that prophylaxis was limited to a single dose in less than half of the procedures [102]. As both the prophylactic and therapeutic use of antibiotics will exert a selective pressure on the bacterial flora of exposed patients, it will be important to improve the prophylactic use of antibiotics in order to reduce the risk of resistance development in the hospital setting [103]. A recent report of a patient with community-acquired pneumonia caused by a levofloxacin-resistant S. pneumoniae illustrates the clinical relevance of any use of antibiotics, as this may result in inadvertent development of resistance in bacteria, which were not the target of the antibiotic prescription [104].…”

Section: Infection Control Measuresmentioning

confidence: 99%