Perioperative Antibiotic Prophylaxis in Ureteroscopic Stone Removal

Knopf, H.-J.; Graff, Heidi J.; Schulze, H.

doi:10.1016/s0302-2838(03)00189-1

Cited by 88 publications

(61 citation statements)

References 4 publications

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“…[29] Biz rutinde olgularımıza operasyon günü sabah ve akşam parenteral birinci kuşak sefalosporin ve takip eden süreçte 3 gün oral sefalosporin antibiyotik tedavisi uyguluyoruz.…”

Section: Discussionunclassified

Effectiveness of 4.5 F semirigid ureteroscope (Mini-URS) in the management of ureteral stones in children younger than 3 years of age

Sancaktutar¹,

Atar²,

Söylemez³

et al. 2011

Turkish Journal of Urology

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“…[29] Biz rutinde olgularımıza operasyon günü sabah ve akşam parenteral birinci kuşak sefalosporin ve takip eden süreçte 3 gün oral sefalosporin antibiyotik tedavisi uyguluyoruz.…”

Section: Discussionunclassified

Effectiveness of 4.5 F semirigid ureteroscope (Mini-URS) in the management of ureteral stones in children younger than 3 years of age

Sancaktutar¹,

Atar²,

Söylemez³

et al. 2011

Turkish Journal of Urology

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“…The incidence of fever in our study, respectively 22.83%, was much higher than the one revealed by Anagnostou et al 2 and slightly smaller than that revealed by Grabe. Paradoxically, if we refer to studies by Knopf 10 and Ramaswamy 18 we notice that the incidence of febrile syndrome was higher in patients who received antibiotic prophylaxis, possibly due to an imbalance of the urinary flora associated with antibiotic administration, or to a non-specific cause of fever.…”

mentioning

confidence: 94%

“…However fever remains the most common postoperative complication. 10 Geavlete et al, in a group of 2735 cases of semirigid ureteroscopy, recorded an incidence of fever in 1.13% of cases; other authors have obtained incidences of up to 6.9%.…”

mentioning

confidence: 94%

“…9 Antibiotic prophylaxis in ureteroscopic stone removal is supported by a randomized trial by Knopf et al in which prophylactic levofloxacin administration significantly reduced postoperative UTIs in healthy population with uninfected preoperative urine and ureteral stones. 10 We performed a study to determine the influence of preoperative prophylaxis in reducing the incidence of post-ureteroscopy fever and its impact in terms of the period of hospitalization. We also tried to identify the influence of certain features of the ureteral stones, such as size, location and overlying distension on the incidence of infectious complications.…”

mentioning

confidence: 99%

“…9,15 However, the risk of nephrotoxicity associated with aminoglycosides limits their use when other active agents are available. Both fluoroquinolones and cephalosporins have proven useful in antibiotic prophylaxis 10,16 without apparent differences in efficacy between these two antibiotic classes.…”

mentioning

confidence: 99%

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Antibiotic prophylaxis in retrograde ureteroscopy: what strategy should we adopt?

Pricop,

Dorobăț,

Puia

et al. 2103

GERMS

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Background Retrograde ureteroscopy as a minimally invasive treatment of ureteral calculi can be complicated by the occurrence of urinary tract infections. Fever is considered the main indicator of such postoperative complications and we aimed to study its incidence in patients with and without preoperative antibiotic prophylaxis.Methods We included all patients who underwent retrograde ureteroscopy for ureteric stones in the Iași and Tg Mureș Urology Clinics from 2009 to 2012. Data were statistically analyzed using the EpiInfo 7 software. Indicative of a statistically significant difference was a p value <0.05.Results We recorded fever in a total of 108 cases, accounting for 22.83% of all subjects in the study. Group 1 included patients who received antibiotic prophylaxis; 48 of 147 (32.65%) were febrile, compared with Group 2 (no antibiotic prophylaxis), where we recorded febrile syndrome in 60 (18.40%) cases, p=0.0009. Comparing the two groups based on calculus size, for stones with diameters of 0.6-0.8 cm 38.71% of patients were febrile in Group 1, compared with 10.88% in Group 2 (p=0.0008). Secondary ureterohydronephrosis did not statistically influence the frequency of fever in any of the studied groups.Conclusion Less than half of all febrile patients had positive urine cultures, which may point to other causes, such as noninfectious factors (aseptic kidney inflammation). This study did not prove the efficiency of preoperative antibiotic prophylaxis; however, based on the clinical experience of the past 120 years, infectious complications are known to be associated with urological maneuvers and prophylaxis could be indicated.

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Infections of the Urinary Tract

1936

JAMA

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Perioperative Antibiotic Prophylaxis in Ureteroscopic Stone Removal

Cited by 88 publications

References 4 publications

Effectiveness of 4.5 F semirigid ureteroscope (Mini-URS) in the management of ureteral stones in children younger than 3 years of age

Effectiveness of 4.5 F semirigid ureteroscope (Mini-URS) in the management of ureteral stones in children younger than 3 years of age

Antibiotic prophylaxis in retrograde ureteroscopy: what strategy should we adopt?

Infections of the Urinary Tract

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