Perioperative Anaphylaxis: Comment

Perioperative Anaphylaxis: Reply

“…We thank the authors of the four letters to the editor 1-4 for their interest in our work regarding our article 5 and would like to respond to them as follows.…”

“…Valach et al 1 suggest intramuscular epinephrine should be used as first-line treatment in perioperative anaphylaxis. We disagree with this suggestion as perioperative anaphylaxis is a life-threatening adverse reaction with an estimated mortality rate of 4 to 4.7%, a mortality rate higher than in food, Hymenoptera, or other drug-related anaphylaxis.…”