Perioperative anaesthetic morbidity in children: a database of 24 165 anaesthetics over a 30‐month period

Murat, I.; Constant, Isabelle; Maud'huy, Hélène

doi:10.1111/j.1460-9592.2004.01167.x

Cited by 444 publications

(401 citation statements)

References 42 publications

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“…6 Re-intubation is not ideal in premature babies where they have often had difficulty weaning them off ventilation initially and who are at greater risk of adverse events from intubation. 2 However, for ROP treatment by laser there is still wide variation in the type of anaesthetic used. In our unit, we use ketamine.…”

Section: Discussionmentioning

confidence: 99%

“…1 Paediatric general anaesthesia carries with it a higher risk of adverse events with particularly high rates in intubated children, the ASA groups 3-4 and neonates. 2 In premature babies, where difficulties are often encountered discontinuing ventilation, the ideal anaesthetic agent causes minimal physiological disturbance avoiding the need for reintubation. Ketamine fulfils this requirement.…”

Section: Introductionmentioning

confidence: 99%

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Ketamine sedation during the treatment of retinopathy of prematurity

Lyon

Dabbs

O'Meara

2007

Eye

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Aims To report the use of ketamine sedation as an alternative anaesthetic method for babies undergoing treatment for retinopathy of prematurity (ROP). Methods All babies who underwent treatment for ROP over a 2-year period were included in this study. The babies preoperative weight, medical condition, and ventilation status was recorded. Data were collected on their ventilation status pre-, intra-, and postprocedure. Any change in their cardiac or respiratory status during or in the subsequent 3 days following the treatment was noted. Results Eleven babies, 22 eyes, required treatment over this period. The procedure was well tolerated with only three babies having intraoperative complications, which all resolved spontaneously. Two babies had postoperative complications requiring additional ventilation. In no case was the procedure abandoned owing to anaesthetic complications. Conclusions The use of ketamine sedation allows the laser to be performed in a ward setting and avoids the potential risk of general anaesthesia and inter-and intra-hospital transfer. It has been found to produce few intra-or postoperative complications for the infant, while providing satisfactory conditions for the treatment of ROP.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Ketamine sedation during the treatment of retinopathy of prematurity

Lyon

Dabbs

O'Meara

2007

Eye

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“…Mamie 9 demonstrated a positive association between airway complications and age < 6 years and Murat 11 observed that respiratory complications were greater in infants compared to children aged 1-7 years.…”

Section: Discussionmentioning

confidence: 99%

“…10 Recurrent infections of the nasal cavity and respiratory tract due to constant irritation and aspiration increase airway reactivity and may result in laryngeal and bronchospasm. 11 Takemura et al 1 defined perioperative respiratory symptoms (PRC) as occurrence of laryngospasm or bronchospasm during induction; increased airway secretions and desaturation (<95%) during maintenance and respiratory symptoms observed immediately after extubation.…”

Section: Introductionmentioning

confidence: 99%

Airway and respiratory complications in children undergoing cleft lip and palate repair

Desalu¹,

Adeyemo²,

Akintimoye³

et al. 2011

Ghana Medical Journal

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“…11,42,47,56 Mortality following anaesthetic-related cardiac arrest is 30% in highincome countries, but far higher in low-income countries. 11,42,47,[56][57][58] Up to 75% of anaesthetic-related cardiac arrests and critical incidents are deemed to be preventable. 11,31,33,42,49,57,59 Anaesthetic-related serious adverse event rates are 1.4 per 1 000 to 1.4 per 10 000 anaesthetics.…”

Section: Incidence Of Morbiditymentioning

confidence: 99%

A review of paediatric anaesthetic-related mortality, serious adverse events and critical incidents

Cronjé

2015

Southern African Journal of Anaesthesia and Analgesia

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Anaesthetists increasingly face questions from parents on the long-term outcomes of anaesthesia, and yet more immediate anaesthetic risks are not understood, nor explained to families. This review focused on paediatric anaesthetic-related mortality, cardiac arrest and anaesthetic-related serious adverse events and critical incidents during general anaesthesia, and within 24 hours of anaesthesia ending. Anaesthetic-related mortality is rare in the developed world, and is approximately 1 per 10 000 anaesthetics, but increases in high-risk children. Serious anaesthetic-related adverse events occur in 1.4 per 1 000 anaesthetics in the developed world. Data are lacking from the developing world but anaesthetic mortality is 2-3 times higher in middle-income countries and may be up to 100-fold greater in low-income countries. A critical incident occurs in 3-8% of anaesthetics and this figure is double that in low-income countries. Anaesthetic-related events are predominantly preventable. Brief recommendations on preventative strategies are made and research goals outlined.

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Perioperative anaesthetic morbidity in children: a database of 24 165 anaesthetics over a 30‐month period

Abstract: This observational study confirms previous reports, and indicates that there is still a relative higher rate of adverse events in infants compared with older children even in a teaching paediatric hospital with a high annual caseload.

Cited by 444 publications

References 42 publications

Ketamine sedation during the treatment of retinopathy of prematurity

Ketamine sedation during the treatment of retinopathy of prematurity

Airway and respiratory complications in children undergoing cleft lip and palate repair

A review of paediatric anaesthetic-related mortality, serious adverse events and critical incidents

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