Perioperative anaesthetic adverse events in Thailand (PAAd THAI) study: Incident report of perioperative convulsion

Abstract

The aim of this study was to identify the characteristics of perioperative convulsion and to suggest possible correcting strategies. The multi-centre study was conducted prospectively in 22 hospitals across Thailand in 2015. The occurrences of perioperative adverse events were collected. The data was collated by site manager and forwarded to the data management unit. All perioperative convulsion incidences were enrolled and analysed. The consensus was documented for the relevant factors and the corrective strategies. Descriptive statistics were used. From 2,000 incident reports, perioperative convulsions were found in 16 patients. Six episodes (37.5%) were related to anaesthesia, 31.3% to patients, 18.8% to surgery, and 12.5% to systemic processes. The contributing factor was an inexperienced anaesthesia performer (25%), while the corrective strategy was improvements to supervision (43.8%). Incidents of perioperative convulsion were found to be higher than during the last decade. The initiation and maintenance of safe anaesthesia should be continued.

Perianesthetic neurological adverse events in children: A review of the Wake‐Up Safe Database

“…Though seizures were the most frequent perioperative central neurological complications in children and adults, the seizure rate of 1 in 100,000 anesthetic encounters in children demonstrated in our study is lower than the rate of 0.5 to 3.1 in 10,000 anesthetic encounters reported in adults 16,17 . It is unlikely that the actual seizure rates are as low as the rates in our study.…”

“…Perioperative central neurological complications have been studied in adults having cardiac, vascular, and noncardiovascular procedures with a detailed evaluation of stroke, seizures, cognitive impairment, and delirium. Nonetheless, a detailed examination of anesthesia‐associated central neurological complications has been limited in children to those having cardiac surgery 8‐21 …”

“…Nonetheless, a detailed examination of anesthesia-associated central neurological complications has been limited in children to those having cardiac surgery. [8][9][10][11][12][13][14][15][16][17][18][19][20][21] Hence, with the aim of better understanding central neurological complications, we reviewed the Wake-Up Safe (WUS) registry to investigate the rate and describe the nature, risk factors, severity of outcome, and contributory and causative factors of NAEs occurring during and within 24 hours of general anesthesia in children.…”