Periodontitis in Patients With Coronary Artery Disease: An 8‐Year Follow‐Up

Abstract

The study results did not show a significant association during 8 years among CAD endpoints and periodontal status at baseline. The progression of periodontitis was low in both groups, although the higher proportion of individuals with severe periodontitis among patients with CAD compared with controls remained unchanged over the 8-year follow-up. Further long-term prospective studies are needed to show whether periodontitis can be considered a risk or prognostic factor for CAD, in terms of endpoints including myocardial infarction, new revascularization procedure, and CAD-related death.

The Association Between Dental Status and Risk of Acute Myocardial Infarction Among Poles: Case-control Study

“…However, not all scientific studies confirm a relationship between periodontitis and MI [18][19][20]. Physicians' Health Study [18] and the National Survey Questionnaire Sweden [19], which included more than 5,000 people, showed no impact of periodontitis on MI.…”

“…Some of them demonstrated that periodontitis constitutes an independent MI risk factor [10][11][12][13][14][15][16][17], whereas other studies did not confirm these relationships [18][19][20]. Therefore, the aim of this study was to answer the question whether the periodontitis severity and extent is an independent and significant risk factor for acute MI in adult Poles under the age of 70 years.…”

Current understanding of the relationship between periodontal and systemic diseases

“…To date, there are no trials that have studied the efficacy of periodontal therapy as a primary preventive intervention for CVD. A somewhat contradictory conclusion supporting a PD/ASD association was reached by Johansson et al 54 who followed patients established histories of ASD and PD for up to 8 years. At the study endpoint, while there was no difference in significant cardiac events between ASD and control patients, at the final periodontal examination, the PD prevalence and severity in ASD patients was significantly higher compared with healthy individuals.…”

Salivary Lipid Peroxidation in Patients With Generalized Chronic Periodontitis and Acute Coronary Syndrome

“…Recent studies have attempted to delineate the relationship between periodontitis and coronary heart disease (CHD) as implied by prior results 4–7 . Among different manifestation levels of CHD, acute coronary syndrome (ACS) represents a spectrum of events ranging from unstable angina pectoris to acute myocardial infarction (AMI), with or without ST elevation 8 .…”