Periodontal disease in gestational and type 1 diabetes mellitus pregnant women

Ruiz, Dóris Rocha; Romito, Giuseppe Alexandre; Dib, Sérgio Atala

doi:10.1111/j.1601-0825.2011.01805.x

Cited by 30 publications

(37 citation statements)

References 45 publications

(66 reference statements)

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“…1). Ten studies [19, 24, 26, 27, 42–47]. that met the eligibility criteria were included in the analysis.…”

Section: Resultsmentioning

confidence: 99%

“…Studies that were excluded were either conducted in diabetic populations other than GDM or lacked relevant information for calculation of risk estimates. Studies were conducted in the USA, [24, 26, 46]; Brazil, [27, 47]; Spain, [43]; Thailand, [19]; Saudi Arabia, [44]; Turkey, [42] and India [45]. There were six case–control studies [19, 26, 27, 42, 45, 47], three cross sectional studies [43, 44, 46] and one cohort study [24].…”

Section: Resultsmentioning

confidence: 99%

“…Definitions used for periodontitis varied widely across studies (Table 1). Seven studies assessed GDM as two or more abnormal values of oral glucose tolerance test (OGTT) [19, 24, 27, 42–44, 47] based on either the O’Sullivan’s [34] or Carpenter and Coustan’s [32] criteria (Table 1). One study [27] defined GDM based on at least one abnormal value of the OGTT [48] and another defined GDM as a positive glucose challenge test [45].…”

Section: Resultsmentioning

confidence: 99%

“…Methodologic quality across case–control and cohort studies was generally high. Six case–control studies and one cohort study were scored either 8 or 7 stars and considered to be of high [19, 24, 26, 27] or medium [42, 47] quality, respectively. One case–control study was noted as having used [45] an inadequate case definition based on the Newcastle Ottawa scale [37], and was considered low in methodologic quality.

Fig.…”

Section: Resultsmentioning

confidence: 99%

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Periodontitis and gestational diabetes mellitus: a systematic review and meta-analysis of observational studies

Abariga

Whitcomb

2016

BMC Pregnancy Childbirth

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BackgroundGestational diabetes mellitus (GDM) is glucose intolerance with first onset during pregnancy and is associated with serious maternal and fetal complications. The etiology of GDM is not well understood, but systemic inflammation effects on insulin signaling and glucose metabolism is suspected. Periodontal disease is a chronic inflammatory condition that induces local and host immune responses and has been evaluated for a potential role in development of GDM. Results from studies evaluating the association between periodontitis and GDM are mixed. We performed a systematic review and meta-analysis to summarize available data regarding the association between periodontitis and GDM.MethodsTwelve electronic databases were searched for observational studies of the association between periodontitis and GDM through March 2016. Eligible studies were assessed for quality and heterogeneity. Random effects models were used to estimate summary measures of association.ResultsWe identified 44 articles from 115 potentially relevant reports of which 10 studies met our eligibility criteria. Clinical diagnostic criteria for periodontitis and GDM varied widely among studies, and moderate heterogeneity was observed. Random effects meta-analysis of all included studies with a total of 5724 participants including 624 cases, showed that periodontitis is associated with an increased risk of GDM by 66 %, (OR = 1.66, 95 % CI: 1.17 to 2.36; p < 0.05), I2 = 50.5 %. Similar results were seen in sub-analysis restricted to data from methodologically high quality case–control studies including 1176 participants including 380 cases, (OR = 1.85, 95 % CI: 1.03 to 3.32); p < 0.05), I2 = 68.4 %. Meta-analysis of studies that adjusted for potential confounders estimated more than 2-fold increased odds of GDM among women with periodontitis (aOR = 2.08, 95 % CI: 1.21 to 3.58, p = 0.009, I2 = 36.9 %).ConclusionMeta-analysis suggests that periodontitis is associated with a statistically significant increased risk for GDM compared to women without periodontitis. Robust prospective study designs and uniform definition for periodontitis and GDM definitions are urgently needed to substantiate these findings.

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“…1). Ten studies [19, 24, 26, 27, 42–47]. that met the eligibility criteria were included in the analysis.…”

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Fig.…”

Section: Resultsmentioning

confidence: 99%

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Periodontitis and gestational diabetes mellitus: a systematic review and meta-analysis of observational studies

Abariga

Whitcomb

2016

BMC Pregnancy Childbirth

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“…связь воспалитель-ных заболеваний пародонта (вЗП) у беремен-ных женщин с сахарным диабетом становится все более актуальной темой для исследований [2,3]. согласно результатам отечественных и зарубежных публикаций, сд у беременных женщин активно влияет на состояние органов полости рта [4,5]. Повышенная концентрация глюкозы в десневой жидкости у пациентов с са-харным диабетом способствует размножению микроорганизмов и быстрому образованию минерализованных и неминерализованных зубных отложений [6].…”

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Clinical and cytological characteristic of a condition of the oral cavity at pregnant women with various types of a diabetes mellitus

Орехова

Aleksandrova

et al. 2016

Z.akus.zen.bolezn

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1 гБОУ вПО «Первый санкт-Петербургский государственный медицинский университет им. и.П. Павлова» Минздрава рФ, санкт-Петербург; 2 ФгБнУ «нии акушерства, гинекологии и репродуктологии им. д.О. Отта», санкт-Петербург; 3 ФгБОУ вО «санкт-Петербургский государственный университет», санкт-Петербург Поступила в редакцию: 01.11.2016 Принята к печати: 05.12.2016 ■ Актуальность. в литературе большое внимание уделяется связи заболеваний ротовой полости у беремен-ных женщин с сахарным диабетом. доказано, что частота кариозного процесса и воспалительных заболеваний пародонта (гингивит и пародонтит) значительно возрастает во время беременности, а наличие сопутствующей патологии, в частности сахарного диабета, является дополнительным неблагоприятным фактором. Цель. Целью работы явилось изучение и сравнение стоматологического статуса беременных женщин при различных типах сахарного диабета с использованием основных и дополнительных клинических методов исследования, а также метода жидкостной цитологии. Материалы и методы. Обследованы женщины с гестационным сахарным диа-бетом, сахарным диабетом 1-го типа, сахарным диабетом 2-го типа и контрольная группа беременных женщин без сахарного диабета. Помимо клинических методов исследования, было произведено цитологическое иссле-дование содержимого зубодесневой борозды методом жидкостной цитологии. Результаты. результаты клини-ческих и лабораторных исследований показали, что воспалительные заболевания пародонта и твeрдых тканей зубов у беременных женщин с сахарным диабетом встречаются чаще, чем у беременных без данной патологии. наибольшая частота встречаемости и тяжесть данных заболеваний отмечается у беременных женщин с сахар-ным диабетом 1-го типа. Заключение. Беременные женщины с сахарным диабетом являются группой риска по воспалительным заболеваниям полости рта и требуют большего внимания со стороны врачей-стоматологов, эндокринологов и акушеров-гинекологов. Применение метода жидкостной цитологии может быть использовано в комплексной оценке воспалительных заболеваний пародонта.■ Ключевые слова: полость рта; беременность; сахарный диабет; воспалительные заболевания пародонта; жидкостная цитология. ■ Introduction. More and more researches dedicated to the communication of diseases of the oral cavity of pregnant women with diabetes. It is proved that the intensity of caries and inflammatory periodontal diseases (gingivitis and periodontitis) increase significantly during pregnancy, while the presence of comorbidities, such as diabetes, increase these indexes. Aim. The aim of the work was to study the dental status of pregnant women with diabetes. Materials and me thods. The study compared women with gestational diabetes mellitus, type 1 diabetes, and type 2 diabetes, to a control group of pregnant women without diabetes. In addition to clinical research methods, liquid-based cytology of the contents of the gingival sulcus was performed. Results. The results of clinical and laboratory studies have shown that inflammatory diseases of periodontium and teeth within pregnant women with d...

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Prenatal Oral Health Education in U.S. Dental Schools and Obstetrics and Gynecology Residencies

Curtis¹,

Silk

Savageau

2013

Journal of Dental Education

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Prenatal oral health (POH) is an important health issue, but dental and obstetrical clinicians are not meeting the oral health needs of pregnant patients. This study evaluates how training contributes to this paradox with a national survey of sixty dental school deans and 240 obstetrics and gynecology residency program directors. Response rates were 53 percent and 40 percent for deans and program directors, respectively. According to the respondents, 94 percent of responding dental schools provided POH education, only 39 percent of responding residencies taught POH, and 65 percent of responding deans and 45 percent of responding program directors were aware of current POH guidelines. The residencies exposing trainees to guidelines were three times more likely to have POH training. Barriers to POH education were reported to include too few pregnant patients in clinical settings (for responding dental schools) and lack of faculty expertise (for responding residencies). The majority of responding deans and program directors agreed they would add more POH education if the American College of Obstetricians and Gynecologists issued a policy statement or practice bulletin. The majority of responding dental deans reported teaching POH in their schools, but clinical exposure was limited; less than half of responding residencies included POH training. Future efforts should include distribution of POH guidelines/consensus statements to educators and learners, increasing exposure of dental students to pregnant patients, and developing faculty expertise in residencies.Dr. Curtis is a family medicine resident, Swedish Family Medicine Residency First Hill, Seattle, WA; Dr. Silk is Clinical Associate Professor,

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Periodontal disease in gestational and type 1 diabetes mellitus pregnant women

Cited by 30 publications

References 45 publications

Periodontitis and gestational diabetes mellitus: a systematic review and meta-analysis of observational studies

Periodontitis and gestational diabetes mellitus: a systematic review and meta-analysis of observational studies

Clinical and cytological characteristic of a condition of the oral cavity at pregnant women with various types of a diabetes mellitus

Prenatal Oral Health Education in U.S. Dental Schools and Obstetrics and Gynecology Residencies

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