Periodontal disease and precursors of oral malodorous components.

Yaegaki, Ken; Suetaka, Takehiko

doi:10.5834/jdh.39.733

Cited by 12 publications

(12 citation statements)

References 11 publications

(1 reference statement)

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“…[3] Some sources of VSC such as bacteria plaque, proteinaceous food debris, and calculus are removed by non-surgical periodontal therapy. [20] This supports a previous study that reported that the level of oral malodor significantly reduced after treating gingival inflammation with scaling and oral hygiene instruction. [21]…”

Section: Discussionsupporting

confidence: 88%

Effect of non-surgical periodontal therapy on the concentration of volatile sulfur compound in mouth air of a group of Nigerian young adults

Ehizele

Akhionbare

2013

Ann Med Health Sci Res

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Background:The major goal of non-surgical periodontal therapy is to reduce or eliminate the subgingival pathogenic microbial flora that is known to be associated with volatile sulfur compounds (VSC).Aim:The aim of this study was, therefore, to determine the effect of non-surgical periodontal therapy on the concentration of VSC in mouth air of young adults.Subjects and Methods:Four hundred subjects, grouped into two based on the absence or presence of periodontal diseases, were involved in this study. Basic periodontal examination was used for the grouping. The measurement of the concentration of the VSC in the mouth air of the subjects was done objectively, using the Halimeter, before and after the therapy, and at recall visits 2 weeks and 6 weeks after therapy. Chi-square and Paired t-test were used to find statistical significance.Results:The results revealed that at baseline, 78.7% (48/61) of the subjects who had VSC concentration more than 250 parts per billion (ppb) were from the group with periodontal disease. Immediately after non-surgical periodontal therapy, only 8.5% (17/200) of the subjects with periodontal disease had VSC concentration of more than 250 ppb while all the subjects with no periodontal disease had VSC concentration less than 181 ppb. The same pattern of reduction in the concentration of the VSC and improvement in oral hygiene was also obtained 2 weeks and 6 weeks after therapy.Conclusion:It can be concluded that non-surgical periodontal therapy brought about reduction in the concentration of volatile sulfur compounds in mouth air of young adults.

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Section: Discussionsupporting

confidence: 88%

Effect of non-surgical periodontal therapy on the concentration of volatile sulfur compound in mouth air of a group of Nigerian young adults

Ehizele

Akhionbare

2013

Ann Med Health Sci Res

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“…Moreover, there is little information in the literature concerning the relationship between precursors of VSC and periodontal disease. 25 We found that the salivary disulfide content increased in patients with periodontal disease, but as disulfide originates from cysteine or cystine, the disulfide content would have no effect on methyl mercaptan production.…”

Section: Gingival Fluidmentioning

confidence: 65%

“…The 10,000 g supernatant was then degassed by aspiration for 5 minutes. Water was added to adjust the original sample volume, 25 µ samples were added with 50 µ 1 M acetate buffer (pH 5.0), and the sample was derivatized with 20 µ 0.1% w/v 3-methyl-2-benzothiazoline hydrazone at room temperature for 30 minutes. The HPLC conditions used were as follows: a Pico tag column1 was eluted at 38°C with buffer A, which consisted of 0.05% triethyl amine, and 5.0% acetonitrile buffered at pH 5.5.…”

Section: Association Between Halitosis and Periodontal Statusmentioning

confidence: 99%

Biochemical and Clinical Factors Influencing Oral Malodor in Periodontal Patients

Yaegaki

Sanada

1992

Journal of Periodontology

Self Cite

268

217

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The amounts of volatile sulfur compounds (VSC) and methyl mercaptan/hydrogen sulfide ratio in mouth air from patients with periodontal involvement were 8 times greater than those of control subjects. Our studies demonstrated that, in patients with periodontal disease: 1) the concentration of disulfide, which is converted to VSC, increased in proportion to the total pocket depth; 2) 60% of the VSC was produced from the tongue surface; 3) the amount of tongue coating was 4 times greater than in control subjects; and 4) VSC production and the methyl mercaptan/hydrogen sulfide ratio of the tongue coating were increased. 2‐Ketobutyrate, which is a byproduct of the metabolism of methionine to methyl mercaptan, was higher in the saliva of patients with periodontal disease. This implies that metabolism of methionine to methyl mercaptan increases in the oral cavity of patients with periodontal pockets. Since free L‐methionine, rather than protein, is the main source for methyl mercaptan, we estimated the methionine supply from the gingival fluid into the oral cavity of patients with periodontal involvement. The results showed that the ratio of methionine to whole free amino acids was significantly higher than that of cysteine. Our studies suggest that not only microorganisms, but also the tongue coating and gingival fluid are factors which enhance VSC production in patients with periodontal disease. J Periodontol 1992; 63:783–789.

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“…There is also general agreement that the VSCs content of exhaled mouth air and the concentration of VSCs precursors increases with the severity of periodontal disease 17,18) . Perry et al 19) .…”

Section: Discussionmentioning

confidence: 76%

Impact of nonsurgical periodontal therapy on oral malodor and microbial load of saliva

Kim

Choi

et al. 2007

J Korean Acad Periodontol

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Periodontal disease and precursors of oral malodorous components.

Cited by 12 publications

References 11 publications

Effect of non-surgical periodontal therapy on the concentration of volatile sulfur compound in mouth air of a group of Nigerian young adults

Effect of non-surgical periodontal therapy on the concentration of volatile sulfur compound in mouth air of a group of Nigerian young adults

Biochemical and Clinical Factors Influencing Oral Malodor in Periodontal Patients

Impact of nonsurgical periodontal therapy on oral malodor and microbial load of saliva

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