Periodontal and chronic kidney disease association: A systematic review and meta‐analysis

Kapellas, Kostas; Singh, Ankur; Bertotti, Maitê; Nascimento, Gustavo G.; Jamieson, Lisa

doi:10.1111/nep.13225

Cited by 56 publications

(90 citation statements)

References 51 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In the KRAM study, 31% of the females and 25% of the males presented ‘good’ oral hygiene (22). Seventy‐nine per cent of the screened patients had gingival inflammatory diseases; for example, gingivitis or periodontitis and four had M‐A‐S‐H, which is in accordance with the conclusion of the recent systematic review and meta‐analysis finding moderate evidence for a positive association between periodontitis and CKD in international studies (7). In this pilot study, 86% of the patients with CKD carried Candida where the carrier rate in the health population is approximately 50% (23).…”

Section: Discussionsupporting

confidence: 87%

“…Periodontal disease and inflammation have been suggested to be associated with cardiovascular diseases in the general population; however, no causality has been shown (6). A recent systematic review and meta‐analysis concluded that there is moderate evidence for a positive association between periodontitis and CKD (7). Patients with CKD often have comorbidities and among these are hypertension, diabetes mellitus and obesity (8).…”

mentioning

confidence: 99%

See 1 more Smart Citation

Oral symptoms and pathologies in Danish patients with chronic kidney disease‐ a pilot study

Kesmez

Frøjk

Eidemak

et al. 2020

APMIS

View full text Add to dashboard Cite

The aim was to investigate oral health in randomly selected patients with chronic kidney disease (CKD). Data obtained by structured interview (self‐reported lifestyle, oral symptoms and regularity of dental visits) and oral examination of patients with CKD from the Copenhagen University Hospital. Fourteen patients with CKD were screened. Only half of the patients reported regular dental visits and poor dental status was registered in half of the patients. Oral mucosal changes were registered in thirteen patients (93%). Eleven patients (79%) had gingival inflammatory disease. Twelve patients (86%) were carriers of Candida, and three (21%) had oral candidosis. Six patients (43%) had low whole saliva flow rate. Twelve patients (86%) reported at least one oral symptom. Overall, there was no differences in oral symptoms or findings related to kidney transplanted or not transplanted patients. The small sample size most likely influences the results. However, the vast majority of patients with CKD reported oral symptoms and only half consulted a dentist regularly. Poor dental status, oral mucosal changes and gingival disease were prevalent findings. Patients with CKD need focus on daily oral healthcare and regular dental visits. Interdisciplinary cooperation could encourage patients with CKD to focus on oral health.

show abstract

Section: Discussionsupporting

confidence: 87%

mentioning

confidence: 99%

Oral symptoms and pathologies in Danish patients with chronic kidney disease‐ a pilot study

Kesmez

Frøjk

Eidemak

et al. 2020

APMIS

View full text Add to dashboard Cite

show abstract

“…In China, the most populous country of Asia comprising 20% of worlds’ population, the estimated prevalence of dialysis patients in 2012 was 215 per million population [ 2 ]. Hemodialysis remains the predominant choice of renal replacement therapy over the options of peritoneal dialysis and kidney transplantation [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

Association of Dose and Frequency on the Survival of Patients on Maintenance of Hemodialysis in China: A Kaplan-Meier and Cox-Proportional Hazard Model Analysis

Sun

Wang

et al. 2018

Med Sci Monit

View full text Add to dashboard Cite

BackgroundDialysis frequency and dose are controversial prognostic factors of hemodialysis morbidity and mortality. The aim of this study was to find out the effect of frequency and dosage of dialysis on mortality and survival in a group of Chinese hemodialysis patients.Material/MethodsIn total, 183 patients seen from February 2008 to January 2018, who were on maintenance hemodialysis for at least 3 months, were included in the study cohort. An anonymized database of age, gender, diabetic status, comorbidities, date of initiation of dialysis, hematological characters, biochemical variables, and status of survived or died was established from DICOM (Digital Imaging and Communications in Medicine) files of patients. Kaplan-Meier and Cox-proportional hazard model was used for calculation of survival over time at 95% confidence level.ResultsOverall, the 10-year survival rate was 27%. Kaplan-Meier analysis showed patient survival as 94% at one-year, 59% at 5-years, and 27% at 10-years. Hemoglobin, serum albumin, calcium, potassium, phosphorous, calcium-phosphorous-products, and hemodialysis frequency and the dose had a significant effect on survival. Cox regression proportional hazard model showed that patients with serum albumin level of >4 g/dL were better associated with survival. Patients who underwent twice-weekly hemodialysis had 4.26 times less chance of survival as compared to patients with thrice-weekly hemodialysis. A higher dialysis dose of >1.2 spKt/V offered better survival as compared to a lower dose of <1.2 spKt/V.ConclusionsHypoalbuminemia, hemodialysis time, and hemodialysis frequency were significantly associated with mortality.

show abstract

“…Estudos sobre a saúde bucal de pacientes com DRC têm avaliado a presença de biofilme dental, cálculo e sangramento gengival (BAYRAKTAR et al, 2008;BOTS et al, 2006;BUHLIN et al, 2007), observando também diferentes alterações nos tecidos periodontais destes pacientes (CASTILLO et al, 2007;KAPELLAS et al, 2019;. A presença de doenças periodontais tem sido investigada como uma potencial fonte de inflamação crônica em pacientes com doença renal crônica tratados por hemodiálise (GARNEATA et al, 2015;KSHIRSAGAR et al, 2007) e em pré-diálise (CHANG et al, 2017;NYLUND et al, 2015;SHARMA et al, 2016).…”

Section: Atuação Do Cirurgião-dentista Na Unidade De Terapia Intensivunclassified

“…Na DP ocorre o desequilíbrio da interação entre espécies bacterianas específicas e os componentes da resposta imunológica em indivíduos susceptíveis (GRUBBS et al, 2016), desencadeia uma superexpressão de citocinas próinflamatórias, incluindo a interleucina-1β (IL-1β), interleucina-6 (IL-6), fator de necrose tumoral-α (TNF-α), e subsequente formação de bolsas periodontais e destruição do tecido conjuntivo de inserção e do osso alveolar (FANG et al, 2015;WAHID et al, 2013 Estudos epidemiológicos têm demonstrado que indivíduos com DRC apresentam higiene bucal deficiente e inflamação periodontal (Bayraktar et al, 2008;Castillo et al, 2007;Kapellas et al, 2019; PALAVRAS-CHAVE: resistência, bactéria, profilaxia, odontologia e antimicrobiano.…”

Section: Atuação Do Cirurgião-dentista Na Unidade De Terapia Intensivunclassified

Alterações Microestruturais Do Esmalte Dentário Submetidos a Imersões Em Águas Saborizadas Ácidas

Espíndola-Castro¹,

Nascimento²,

Celerino³

et al. 2020

Odontologia: Serviços Disponíveis E Acesso 3

View full text Add to dashboard Cite

Todo o conteúdo deste livro está licenciado sob uma Licença de Atribuição Creative Commons. Atribuição 4.0 Internacional (CC BY 4.0). O conteúdo dos artigos e seus dados em sua forma, correção e confiabilidade são de responsabilidade exclusiva dos autores. Permitido o download da obra e o compartilhamento desde que sejam atribuídos créditos aos autores, mas sem a possibilidade de alterá-la de nenhuma forma ou utilizá-la para fins comerciais.

show abstract

Periodontal and chronic kidney disease association: A systematic review and meta‐analysis

Abstract: Moderate evidence for a positive association between periodontitis and CKD exists. Evidence for the opposite direction is extremely weak based on significant heterogeneity between studies.

Cited by 56 publications

References 51 publications

Oral symptoms and pathologies in Danish patients with chronic kidney disease‐ a pilot study

Oral symptoms and pathologies in Danish patients with chronic kidney disease‐ a pilot study

Association of Dose and Frequency on the Survival of Patients on Maintenance of Hemodialysis in China: A Kaplan-Meier and Cox-Proportional Hazard Model Analysis

Alterações Microestruturais Do Esmalte Dentário Submetidos a Imersões Em Águas Saborizadas Ácidas

Contact Info

Product

Resources

About