Periodized home-based training: A new strategy to improve high intensity exercise therapy adherence in mildly affected patients with Multiple Sclerosis

Adherence and drop-out in randomized controlled trials of exercise interventions in people with multiple sclerosis: A systematic review and meta-analyses

“…Although not included in this review, it is encouraging that more recent pilot and feasibility studies [69][70][71] are seeking to further evaluate the addition of such interventions which may provide useful future insights.…”

Blood lactate concentrations during rest and exercise in people with Multiple Sclerosis: A systematic review and meta-analysis

“…With 1 exceptional outlier with a sample size totalling 1238 participants (613 with MS) [7], 6 studies had less than 30 participants [23][24][25]28,33,36], 9 studies had between 30 and 70 participants [17][18][19]26,27,29,32,34,35] and 2 studies had between 100-110 participants [30,31]. The total number of participants reported on across all studies was 1986; 1129 were participants with MS. 5 papers failed to adequately describe their methods adequately for study reproduction [23,24,30,31,33].…”

Home-Based Tele-Exercise in Musculoskeletal Conditions and Chronic Disease: A Literature Review

“…One directly monitored study in individuals with MS utilized a home-based, high intensity cycling program with the intention of improving fitness, exercise capacity, and body composition. Participants with MS and healthy controls had similar significant improvements in peak VO 2 , while significant reductions in body mass were observed only in individuals with MS (108). One more RCT in individuals with MS compared a supervised telerehabilitation program to both an in-person rehabilitation program and an un-supervised home-based exercise program acting as a control group.…”

“…Studies that have examined tele-exercise interventions in individuals with MS have used a variety of methods, including aerobic training ( 105 – 108 ), strength training ( 105 – 107 , 109 ), balance exercises ( 105 , 106 ), and physical therapy exercises ( 110 ). A pilot study of home-based telerehabilitation in individuals with MS used an indirectly supervised program of strength, stretching, and balance exercises customized to each participant, and found significant improvements in outcomes such as 25 ft walk time, 6MWD, and balance.…”