Periodical changes of input air flowrate – a possible way of improvement of oxygen transfer and liquid circulation in airlift bioreactors

Godó, Š.; Klein, Jaroslav; Polakovič, Milan; Báleš, V.

doi:10.1016/s0009-2509(99)00215-8

Cited by 14 publications

(12 citation statements)

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“…However, the downcomer bubbles reduce the density difference between the riser and downcomer decreasing thereby the circulation rate. Godo et al (1999) observed the decrease in circulation rate. Halting the air fl ow dissipated foam at the top and permitted small bubbles to fl oat out of the downcomer.…”

Section: Flow Interruptionmentioning

confidence: 92%

“…In the above balances 1 = hydrogen, 2 = phenylacetylene, 3 = styrene and 4 = ethylbenzene The explanation offered by Godo et al (1999) for the surprising augmentation of dissolved O 2 is that sparging the high viscosity, pseudo plastic culture produced large bubbles and slug fl ow in the riser and a relatively low interfacial area. Foam developed at the top and a portion was drawn into the downcomer forming fi ne bubbles that attach to the downcomer walls.…”

Section: Flow Interruptionmentioning

confidence: 99%

“…Is the phenomenon observed by Godo et al (1999) general or is it a specifi c characteristic of the mould and operating conditions that these investigators used ? If it is indeed general, then periodic air fl ow variation could be a useful tool for increasing fermentation or cell culture throughput.…”

Section: Flow Interruptionmentioning

confidence: 99%

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Periodic Operation of Three — Phase Catalytic Reactors

Silveston

Hanika

2004

Can J Chem Eng

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Periodic operation of three phase reactors has been explored for more than two decades. This type of forcing changes selectivity and can increase either conversion or throughput. Experiments and simulation demonstrate periodic flow interruption or variation enhances reaction rates for concurrent trickle beds provided reactants are in the gas phase or can be volatilized under bed operating conditions. Temperature excursions in trickle beds can be controlled by either flow variation or switching the feed between an inert and a reactant. Several approaches to increasing rate through faster mass transfer using flow pulsing have been studied. Pulsing flow can be induced by low amplitude modulation. Periodic switching of flow direction in airlift reactors increases gas hold up and thereby the mass transfer rate. Periodic operation of three phase reactors, thus, appears to be a fertile area for engineering research.

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Section: Flow Interruptionmentioning

confidence: 92%

Section: Flow Interruptionmentioning

confidence: 99%

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Periodic Operation of Three — Phase Catalytic Reactors

Silveston

Hanika

2004

Can J Chem Eng

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“…However, several techniques were applied to enhance the oxygen transfer rates in columns at low aeration rates (Fraser and Hill, 1993;Godo et al 1999;Su and Heindel, 2004), but the oxygen transfer coefficient was significantly increased by adding packing into the column (Moraveji et al, 2011a). Nikakhtari and Hill (2005) used stainless steel meshes as a packing with 99.0% porosity in the riser section of an external loop airlift bioreactor (ELAB).…”

Section: Introductionmentioning

confidence: 99%

Hydrodynamics and oxygen mass transfer characteristics of petroleum based micro-emulsions in a packed bed split-cylinder airlift reactor

Moraveji

Mohsenzadeh

Fakhari

et al. 2013

Braz. J. Chem. Eng.

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-The effects of aeration velocity and liquid properties on the pertinent hydrodynamic and mass transfer parameters in a split-cylinder airlift reactor (with and without packing) were examined. Four different oil-in-water micro-emulsion systems containing kerosene, heavy naphtha, light naphtha and diesel as the oil at the concentration of 7% (v/v) were used in the experiments and the results were compared with pure water. The experimental results showed that the gas (air) hold-up and the volumetric gas-liquid oxygen transfer coefficient values for the micro-emulsion systems were usually greater than those of pure water. The packing installation increased the overall gas-liquid volumetric mass transfer coefficient by increasing the flow turbulence and Reynolds number, compared to the unpacked column. The packing increased the gas hold-up and decreased the bubble size and liquid circulation velocity. Furthermore, two empirical correlations were developed to predict the overall gas hold-up and volumetric oxygen transfer coefficient. A good agreement was observed between the experimental and correlated data.

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“…Practical importance of slug regime is low. But if the liquid phase changes its physico-chemical properties during the process in such a way that the initially Newtonian behaviour changes into non-Newtonian (as a result of the biomass growth), then churn flow may transform into slug flow (see Godó, et al (1999) ).…”

mentioning

confidence: 99%

Optimal Design of a Multifunctional Reactor for Catalytic Oxidation of Glucose with Fast Catalyst Deactivation

Gogová¹

2010

Dynamic Modelling

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Periodical changes of input air flowrate – a possible way of improvement of oxygen transfer and liquid circulation in airlift bioreactors

Cited by 14 publications

References 0 publications

Periodic Operation of Three — Phase Catalytic Reactors

Periodic Operation of Three — Phase Catalytic Reactors

Hydrodynamics and oxygen mass transfer characteristics of petroleum based micro-emulsions in a packed bed split-cylinder airlift reactor

Optimal Design of a Multifunctional Reactor for Catalytic Oxidation of Glucose with Fast Catalyst Deactivation

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