The aim of this work is to study the existence of a periodic solutions of differential equations The aim of this paper is to study the existence and uniqueness of solutions for some differential equations by using methods of maximal regularity in spaces of Besov space. Motivated by the fact that functional differential equations arise in many areas of applied mathematics, this type of equations has received much attention in recent years. In particular, the problem of existence of periodic solutions, has been considered by several authors. We refer the readers to papers (Arendt, W. & Bu, S., 2004; Hernan, R. H., 2012;Keyantuo, V. & et al., 2009) and the references listed therein for information on this subject. One of the most important tools to prove maximal regularity is the theory of Fourier multipliers. They play an important role in the analysis of parabolic problems. In recent years it has become apparent that one needs not only the classical theorems but also vector-valued extensions with operator-valued multiplier functions or symbols. These extensions allow to treat certain problems for evolution equations with partial differential operators in an elegant and efficient manner in analogy to ordinary differential equations. For some recent papers on the subjet, we refer to Poblete (2009), Lizama (2006), Hernan (2012), and Arendt-Bu (2004). We characterize the existence of periodic solutions for the following integro-differential equations in vector-valued spaces and Besov. Our results involve only M-boundedness of the resolvent.In this work, we study the existence of periodic solutions for the following differential equationswhere A : D(A) ⊆ X → X is a linear closed operator on Banach space (X, ∥.∥), and f ∈ L p (T, X) for all p ≥ 1.For example:In (