Periodic nanohole arrays with shape-enhanced plasmon resonance as real-time biosensors

Lesuffleur, Antoine; Im, Hyungsoon; Lindquist, Nathan C.; Oh, Sang‐Hyun

doi:10.1063/1.2747668

Cited by 269 publications

(194 citation statements)

References 18 publications

Supporting

Mentioning

184

Contrasting

Unclassified

Order By: Relevance

“…Alignment is an expensive, time-consuming process, rendering such sensors unsuitable for point-of-care applications. Sensors based on nanoplasmonics, on the other hand, are tolerant regarding alignment and still show impressive sensitivities [22][23][24][25][26][27][28].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Photonic-crystal membranes for optical detection of single nano-particles, designed for biosensor application

Grepstad¹,

Kaspar²,

Solgaard³

et al. 2012

Opt. Express

View full text Add to dashboard Cite

Abstract:A sensor designed to detect bio-molecules is presented. The sensor exploits a planar 2D photonic crystal (PC) membrane with sub-micron thickness and through holes, to induce high optical fields that allow detection of nano-particles smaller than the diffraction limit of an optical microscope. We report on our design and fabrication of a PC membrane with a nano-particle trapped inside. We have also designed and built an imaging system where an optical microscope and a CCD camera are used to take images of the PC membrane. Results show how the trapped nano-particle appears as a bright spot in the image. In a first experimental realization of the imaging system, single particles with a radius of 75 nm can be detected.

show abstract

Section: Introductionmentioning

confidence: 99%

“…Some of the most sensitive biosensors with optical readout today are based on dielectric photonic crystals (PCs) [16][17][18][19][20][21] and nanoplasmonics [22][23][24][25][26][27][28]. They all rely on surface chemistry to capture specific target molecules.…”

Section: Introductionmentioning

confidence: 99%

Photonic-crystal membranes for optical detection of single nano-particles, designed for biosensor application

Grepstad¹,

Kaspar²,

Solgaard³

et al. 2012

Opt. Express

View full text Add to dashboard Cite

show abstract

“…[19] To demonstrate the potential of the nanograil as a label-free, real-time biosensor, a gold nanograil array with a maximum S bulk of %1400 nm/RIU was exposed to 0.2 wt % bovine serum albumin (BSA) in phosphate-buffered saline (PBS) solution. [20] Figure 5c shows the real-time dip change of the J 1 plasmon induced by adsorbed BSA onto the nanograil surface. The J 1 mode red-shift was saturated at %11 nm after %500 s. This red-shift of %11 nm is approximately 2À4 times larger than those reported for gold nanoring and nanoslit arrays, [19,20] which can partly be attributed to the exceptionally high bulk refractive-index sensitivity of the nanograil used in this experiment.…”

mentioning

confidence: 98%

“…[20] Figure 5c shows the real-time dip change of the J 1 plasmon induced by adsorbed BSA onto the nanograil surface. The J 1 mode red-shift was saturated at %11 nm after %500 s. This red-shift of %11 nm is approximately 2À4 times larger than those reported for gold nanoring and nanoslit arrays, [19,20] which can partly be attributed to the exceptionally high bulk refractive-index sensitivity of the nanograil used in this experiment.…”

mentioning

confidence: 98%

Gold “Nanograils” with Tunable Dipolar Multiple Plasmon Resonances

et al. 2009

View full text Add to dashboard Cite

In the emerging field of plasmonics, [1] there has been much research interest in various kinds of metal nanostructures, in which confined electrons are forced to oscillate by an incident electromagnetic wave; the resulting electron oscillation can exhibit strong local-field enhancement at a particular resonant frequency. Such electron-photon coupled resonances, known as localized surface plasmon resonances (LSPRs), have resulted in unique, promising applications ranging from photonics to biotechnology.[2] The strongly enhanced electromagnetic field around metal nanostructures is essential to increase nearly all light-matter interactions including surface-enhanced Raman scattering (SERS).[3] According to the plasmon hybridization model, [4] the plasmon resonance frequency is largely determined by the geometry of the metal structure itself, as a result of electrostatic interactions between confined electrons distributed over the surfaces of the metal conductor. It is also known that the plasmon resonance is scale-invariant, implying that metal nanostructures with the same shape but of different sizes will have essentially the same LSPR frequencies. [5] Tunable plasmon resonances, together with enhanced local electromagnetic fields, are of practical importance for high fidelity biochemical sensors. Thus, metal nanoparticles with various shapes, including nanoshells, [6] nanorings, [7] nanorods, [8] and nanorices [9] have been proposed for exploiting the full potential of the geometry-dependent LSPRs. In shell-type geometries such as nanoshells and nanorings, interactions among electrons bound to the inner and outer surfaces of the shell give rise to so-called plasmon hybridization, resulting in a wide range of tunability. [4] Nanocrescent moon structures that combine the geometrical features of both nanorings and nanotips can exhibit very strong local fields around the sharp edge of a shell opening.[10] Arrays of individual plasmon nanostructures are also of special interest in the context of local field enhancement. For example, it is possible to utilize a local hot spot at the junction of a dimmerlike coupled structure or long-range dipolar interactions to obtain further enhancement of the local fields.[11]Here, we report novel metallic nanostructures that share the features of shell-type plasmon geometries mentioned above. As shown in Figure 1a and b, the proposed structure is a vertically arranged ring with a varying diameter. The overall structural shape is featured as three rings with sharp edges (a typical ring diameter is several hundred nanometers) and is similar in appearance to a grail; hence the name 'nanograil.' For this geometry, three types of strong plasmon resonances coupled with each other at their respective edges are expected. As described below, these plasmon resonances can be controlled by varying the fabrication conditions in order to modify the geometrical features of the nanograil, which results in tunable LSPRs spanning from 600 to 2 000 nm. Furthermore, considerably large local-field enha...

show abstract

“…In recent years, periodic nanostructures are of great scientific interest and considerable technological importance and have been extensively investigated to meet the stringent requirement for many emerging applications, including biomedical sensors [1][2][3], phonics crystals [4,5], photovoltaic devices [6,7], surface plasmon resonance (SPR) sensors or surface-enhanced Raman scattering (SERS) [8][9][10], as well as nanoimprint template [11,12]. There are numerous fabrication techniques and methods to produce periodic nanostructures of Si and SiO2 using top-down or bottom-up patterning strategies in the literatures.…”

Section: Introductionmentioning

confidence: 99%

CMOS-Compatible Top-Down Fabrication of Periodic SiO2 Nanostructures using a Single Mask

Meng¹,

Gao²,

He³

et al. 2016

Nano Online

View full text Add to dashboard Cite

(http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.We propose a CMOS-compatible top-down fabrication technique of highly-ordered and periodic SiO2 nanostructures using a single amorphous silicon (α-Si) mask layer. The α-Si mask pattern is precisely transferred into the underlying SiO2 substrate material with a high fidelity by a novel top-down fabrication. It is the first time for α-Si film used as an etch mask to fabricate SiO2 nanostructures including nanoline, nanotrench, and nanohole arrays. It is observed that the α-Si mask can significantly reduce the pattern edge roughness and achieve highly uniform and smooth sidewalls. This behavior may be attributed to the presence of high concentration of dangling bonds in α-Si mask surface. By controlling the process condition, it is possible to achieve a desired vertical etched profile with a controlled size. Our results demonstrate that SiO2 pattern as small as sub-20 nm may be achievable. The obtained SiO2 pattern can be further used as a nanotemplate to produce periodic or more complex silicon nanostructures. Moreover, this novel top-down approach is a potentially universal method that is fully compatible with the currently existing Si-based CMOS technologies. It offers a greater flexibility for the fabrication of various nanoscale devices in a simple and efficient way.

show abstract

Periodic nanohole arrays with shape-enhanced plasmon resonance as real-time biosensors

Cited by 269 publications

References 18 publications

Photonic-crystal membranes for optical detection of single nano-particles, designed for biosensor application

Photonic-crystal membranes for optical detection of single nano-particles, designed for biosensor application

Gold “Nanograils” with Tunable Dipolar Multiple Plasmon Resonances

CMOS-Compatible Top-Down Fabrication of Periodic SiO2 Nanostructures using a Single Mask

Contact Info

Product

Resources

About