Periodic fluctuations of streamwise vortices in inertia-dominated intersecting flows

Burshtein, Noa; Zografos, Konstantinos; Shen, Amy Q.; Poole, Robert J.; Haward, Simon J.

doi:10.1063/5.0031712

Cited by 19 publications

(15 citation statements)

References 82 publications

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“…Previous studies have demonstrated that the simulation method used in current study is suitable for steady and unsteady inertial vortical flows in micro mixers, especially for steady engulfment flows. ,,, In current work, on the basis of previous work, ,, the applicability of the adopted simulation method for the unsteady flows is further validated. As shown in Figure S2, experimental and simulated dye concentrations on plane z / h = 0 for w i / h = 0.3 and Re = 400 at five moments in a period are compared.…”

Section: Numerical Methodologymentioning

confidence: 88%

“…It should be pointed out that flow regimes are also sensitive to geometrical parameters of cross-shaped mixers. ,− By 2D and 3D numerical simulations, Correa et al , analyzed the influence of w i / h and crossing angles (the angle between the inlet channel and the mixing chamber) on the development of vortices in cross-shaped mixers. It was found that, as w i / h increases from 1 to 11, the number of vortices increases from 1 to 4.…”

Section: Introductionmentioning

confidence: 99%

“…As the crossing angle is greater than 60°, three-dimensional flows in the mixing chamber cannot be reproduced by a 2D simulation. Burshtein et al studied the characteristics of pulsation flows in cross-shaped mixers for w i / h = 0.45, 1, and 2.4, and asymmetric vortex merging was observed in the mixing chamber for w i / h = 0.45. The above investigations indicated that flow regimes in cross-shaped mixers depend on Reynolds number and geometrical parameters.…”

Section: Introductionmentioning

confidence: 99%

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Effect of Chamber Depth Modifications on Flow Regimes and Mixing Performance in Cross-Shaped Mixers

Zhang

Feng²,

et al. 2022

Ind. Eng. Chem. Res.

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Flow and mixing in cross-shaped mixers with various chamber depths (w i /h, in which w i and h are the chamber depth and inlet height, respectively) were studied by Plane Laser-Induced Fluorescence (PLIF) and numerical simulation at 20 ≤ Re ≤ 500. Emphasis was placed on engulfment flows and pulsation flows, as well as the dominant role of vortices and their dynamic evolution. For w i /h > 0.3, segregated flows, steady engulfment flows, pulsation flows, and unsteady engulfment flows emerge successively with increasing Reynolds number (Re = ρu 0 D h/μ, where ρ, μ, D h, and u 0 are the fluid density, fluid viscosity, inlet hydraulic diameter, and inlet bulk mean velocity, respectively). As w i /h decreases, engulfment and pulsation flows are delayed, and the recirculation regions induced by vortex breakdown are shifted. For w i /h ≤ 0.3, pulsation flows and recirculation regions disappear, and a hybrid mode of deflecting oscillation and vortex merging is identified. The degree of mixing was quantitatively analyzed to reveal the mixing mechanism. At low Re, an increase in w i /h improves the mixing due to the earlier onset of steady engulfment flows. For higher Re, better mixing appears for w i /h ≤ 0.3 attributed to vortex merging and deflecting oscillations.

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Section: Numerical Methodologymentioning

confidence: 88%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Effect of Chamber Depth Modifications on Flow Regimes and Mixing Performance in Cross-Shaped Mixers

Zhang

Feng²,

et al. 2022

Ind. Eng. Chem. Res.

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“…Second, streamwise vortices are known to develop in water downstream of the cross junction at moderately high Reynolds numbers (onset Re = 107 for a channel height to width ratio of 0.45) comparable to those used in the current study. 38 The presence of such asymmetric vortices could lead to asymmetric splitting of cells. When cell splitting was performed at a Reynolds number of 346 ( v e = 2.08 m/s), we noticed that in some cases, there was flapping of the “tail” region of the fragment immediately following the split (Movie S1).…”

Section: Resultsmentioning

confidence: 99%

Hydrodynamic dissection of single cells in a microfluidic system

Paul

Zhang

Jalil

et al. 2022

Preprint

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Stentor coeruleus, a single-cell ciliated protozoan, is a model organism for wound healing and regeneration studies. Despite Stentor's large size (up to 2 mm in extended state), microdissection of Stentor remains challenging. In this work, we describe a hydrodynamic cell splitter, consisting of a cross junction, capable of splitting Stentor cells in a non-contact manner at a high throughput of ~500 cells/min under continuous operation. Introduction of asymmetry in the flow field at the cross junction leads to asymmetric splitting of the cells to generate cell fragments as small as ~8.5 times the original cell size. Characterization of cell fragment viability shows reduced 5-day survival as fragment size decreases and as the extent of hydrodynamic stress imposed on the fragments increases. Our results suggest that cell fragment size and composition, as well as mechanical stress, play important roles in the long-term repair of Stentor cells and warrant further investigations. Nevertheless, the hydrodynamic splitter can be useful for studying phenomena immediately after cell splitting, such as the closure of wounds in the plasma membrane which occurs on the order of 100- 1000 seconds in Stentor.

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“…Second, streamwise vortices are known to develop in water downstream of the cross junction at moderately high Reynolds numbers (onset Re = 107 for a channel height to width ratio of 0.45) comparable to those used in the current study. 49 The presence of such asymmetric vortices could lead to asymmetric splitting of cells. When cell splitting was performed at a Reynolds number of 346 (v e = 2.08 m s −1 ), we noticed that in some cases, there was flapping of the "tail" region of the fragment immediately following the split (Movie S1 †).…”

Section: Characterization Of Splitting Probability and Symmetrymentioning

confidence: 99%