Periocular ecthyma gangrenosum in a diabetic patient

Inamadar, Arun C; Palit, Aparna; Athanikar, S. B.; Sampagavi, V. V.; Deshmukh, N. S.

doi:10.1046/j.1365-2133.2003.05183.x

Cited by 8 publications

(4 citation statements)

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“…described a diabetic individual who developed severe periorbital EG after suffering a laceration to the forehead. [ 9 ] Ghosheh and Kathuria reported a case of bilateral periorbital EG in a diabetic male with renal failure. [ 5 ] The mortality rate in nonsepticemic cases varies between 0% and 15% compared with 20–96% for those associated with septicemia.…”

Section: Discussionmentioning

confidence: 99%

Nonpseudomonal ecthyma gangrenosum of the upper lid treated with lid reconstruction

Kumar

Kaliaperumal

et al. 2015

Indian J Ophthalmol

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Ecthyma gangrenosum (EG) is a cutaneous infection which usually occurs in immunocompromised patients. We report a case of EG of the eyelid treated with escharotomy and skin grafting, highlighting the importance of surgical management. A 2-year-old Asian Indian female presented to us with right upper lid edema with a large necrotic area. The child received intravenous cefotaxime for a week and the necrotic area turned to a well-defined eschar. Escharotomy with wound debridement and skin grafting was done. The present case highlights the importance of surgical intervention to prevent the sequelae of scarring of upper lid.

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Section: Discussionmentioning

confidence: 99%

Nonpseudomonal ecthyma gangrenosum of the upper lid treated with lid reconstruction

Kumar

Kaliaperumal

et al. 2015

Indian J Ophthalmol

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“…The trunk, arms, and face are less often involved. 9 EG results from pathogen invasion of the skin and subcutaneous tissue veins and arteries walls. This phenomenon can come from within the vessel, as a consequence of septicaemia, or by direct cutaneous inoculation.…”

Section: The Answer and A Short Explicative Text Ecthyma Gangrenosum ...mentioning

confidence: 99%

Rapidly progressive necrotic ulcers in an immunocompetent patient

Freitas¹,

Lé²,

Velho³

2022

JDC

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“…The lesions occur mainly in the perineal region (57%), but may also arise on the extremities (30%), trunk (6%) and face (6%) 2 . Typically, EG occurs in immunosuppressed patients with leukemia 3 or AIDS, 4,5 in organ transplant recipients, 6,7 and in patients with agammagloblinemia, 8 hypogammaglobulinemia 9 and diabetes, 10 and the lesions are frequently associated with poor prognosis and high mortality. However, EG lesions sometimes occur in healthy people 11,12 and cases without septicemia due to P. aeruginosa are also occasionally found 3,13 .…”

Section: Introductionmentioning

confidence: 99%

Ecthyma gangrenosum without pseudomonas septicemia in a kidney transplant recipient

Nakai

Takenaka

Kishimoto

2008

The Journal of Dermatology

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We report a case of ecthyma gangrenosum (EG) without septicemia in a renal transplant recipient who presented with a 1-month history of painful ulcers, vesicles and bullae on the face and extremities. Histopathological findings revealed subepidermal bullae covered by a necrotic epidermis containing an infiltrate of a moderate number of lymphocytes, neutrophils and necrotic collagen. Many dilated and congested capillaries were also present due to thrombi beneath the bullae, with alteration of collagen fibers through the superficial to middle dermis with some infiltrate. A culture from the ulcers revealed the presence of Pseudomonas aeruginosa and methicillin-resistant Staphylococcus aureus, whereas the results of repeated blood cultures were negative. The ulcers were completely cured by early appropriate i.v. antibiotic therapy with granulocyte colony-stimulating factor, without progression to EG with septicemia. An immunocompromised state due to immunosuppressive drugs, in addition to diabetes mellitus, hypogammaglobulinemia and hypoproteinemia, may have caused the EG and herpes zoster may have exacerbated the condition.

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Periocular ecthyma gangrenosum in a diabetic patient

Cited by 8 publications

References 0 publications

Nonpseudomonal ecthyma gangrenosum of the upper lid treated with lid reconstruction

Nonpseudomonal ecthyma gangrenosum of the upper lid treated with lid reconstruction

Rapidly progressive necrotic ulcers in an immunocompetent patient

Ecthyma gangrenosum without pseudomonas septicemia in a kidney transplant recipient

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