Perineural infiltration of the inferior alveolar nerve in mandibular ameloblastomas

Engelbrecht, H.; Meer, Shabnum; Kourie, Jeff F.

doi:10.1016/j.bjoms.2013.02.002

Cited by 10 publications

(9 citation statements)

References 20 publications

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“…Ameloblastoma is the most common benign odontogenic tumor with an origin of epithelium to affect the mandible, 19 accounting for about 1% of all tumors and cysts involving the jaws. Approximately 80% of ameloblastomas occur in the lower jaw, mainly in the third molar region.…”

Section: Discussionmentioning

confidence: 99%

The effect of ameloblastoma and keratocystic odontogenic tumor on the displacement pattern of inferior alveolar canal in CBCT examinations

Abdi¹,

Talesh²,

Yazdani³

et al. 2016

J Dent Res Dent Clin Dent Prospects

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Background. The inferior alveolar canal should be examined as a significant anatomical landmark, particularly in the posterior body and ramus of the mandible, for dental and surgical procedures. In the present study, the effects of two pathological lesions, ameloblastoma and keratocystic odontogenic tumor, on canal displacement were investigated.Methods. This study had a single-blinded design. Twenty-six patients with lesions in the mandible referred to Imam Reza Hospital, Tabriz, Iran, were studied in two equal groups (13 patients with a histopathological diagnosis of ameloblastoma and 13 with a histopathological diagnosis of odontogenic keratocyst). After confirming the initial incisional biopsy and pathological report, cone beam computed tomography (CBCT) of lesions larger than 3 cm mesiodistaly and those involving the mandibular posterior body and ramus were included in the study. Two maxillofacial surgeons in association with an oral and maxillofacial radiologist examined three points on CBCT images to determine the mandibular canal position relative to the lesions from the lingual and buccal aspects.Results. The results of statistical analyses showed that in ameloblastoma, the inferior alveolar canal had been displaced more buccally in the ramus area (point A) (84.6%) but in the distal region (point C), the displacement was less buccal (41.6%). The canal was displaced buccally in 53.8% of cases at point A and in 46.2% of cases at point C in KOT lesions. Finally chi-squared test did not show any statistically significant differences between these two lesions.Conclusion. The results of this study showed no relationship between these lesions and the displacement of the mandibular canal.

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Section: Discussionmentioning

confidence: 99%

The effect of ameloblastoma and keratocystic odontogenic tumor on the displacement pattern of inferior alveolar canal in CBCT examinations

Abdi¹,

Talesh²,

Yazdani³

et al. 2016

J Dent Res Dent Clin Dent Prospects

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“…However, for large aggressive tumors, Engelbrecht et al found in a histopathological study of resection specimens that the tumors not only abut the nerve sheath but invade the inferior alveolar nerve and they could not recommend preservation for larger aggressive tumors. 18 Similarly, Nakamura et al also concluded that preservation of the nerve may be possible in management of unicystic lesions but that multicystic or solid tumors, especially the follicular variant, require a more radical approach with probable sacrifice of the nerve bundle as perineural invasion was identified on histopathologic specimens. 19 Others argue that although bony destruction of the mandibular canal may be present with follicular and plexiform variants, no invasion of the nerve sheath or nerve occurs and therefore advocate for a less aggressive approach.…”

Section: Managementmentioning

confidence: 96%

“…1,3,4 Though their recurrence rate and treatment has been debated in the literature with some reporting recurrence rates as high as 64% after simple enucleation and currettage, 17 most recommend conservative therapy and close follow up with aggressive treatment saved for recurrence. 18 The exception is for the intraluminal and intramural subtypes where aggressive surgical resection is advocated. 2,5,13 Peripheral ameloblastomas are often clinically innocuous and respond well to local surgical excision.…”

Section: Managementmentioning

confidence: 99%

Management of ameloblastoma in the pediatric population

Payne

Albert

Lighthall

2015

Operative Techniques in Otolaryngology-Head and Neck Surgery

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“…Recent studies have confirmed the presence of perineural and intraneural involvement of the ameloblastoma with the nerve and recommended that the nerve should not be preserved in cases of advanced mandibular ameloblastoma. [40] Radiotherapy was also reported as a treatment modality of ameloblastoma especially as a salvage therapy. [41,42]…”

Section: Treatmentmentioning

confidence: 99%

Ameloblastoma: A clinical study of 25 Iraqi patients

Bede

Mohammed²,

Hasan³

2016

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Objective: Geographic differences in clinical and pathological aspects of ameloblastoma have been suggested, therefore the purpose of this study was to analyze cases of ameloblastoma in terms of clinical and radiographic manifestations, histopathological types, treatment modalities and recurrence rate and compare them with reports from other parts of the world. Methods: The medical reports of patients diagnosed with ameloblastoma were reviewed and the data concerning the age, gender, chief complaint, the anatomical site of the lesion, radiographic appearance, histopathological diagnosis, treatment approach and recurrence were retrieved. Surgical treatment consisted of either enucleation with curettage and peripheral ostectomy or resection; marginal or segmental. Statistical analysis included descriptive and inferential statistics. Results: This study included 25 patients with a mean age of 39 years, 14 (56%) were males and 11 (44%) were females. Six patients (24%) were below 20 years when diagnosed. Nineteen patients (76%) had Solid Ameloblastoma, while the remaining 6 patients (24%) were diagnosed with Unicystic ameloblastoma, surgical treatment was provided for 23 patients, recurrence occurred in 2 patients (8.7%). Conclusions: The main clinical characteristics of ameloblastoma in Iraq are in line with those reported in other studies from other parts of the world especially Asian countries, being mostly of solid variant, predominantly involving the mandibular posterior region, with no gender predilection or slight male preponderance but generally affecting younger age group.

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Perineural infiltration of the inferior alveolar nerve in mandibular ameloblastomas

Cited by 10 publications

References 20 publications

The effect of ameloblastoma and keratocystic odontogenic tumor on the displacement pattern of inferior alveolar canal in CBCT examinations

The effect of ameloblastoma and keratocystic odontogenic tumor on the displacement pattern of inferior alveolar canal in CBCT examinations

Management of ameloblastoma in the pediatric population

Ameloblastoma: A clinical study of 25 Iraqi patients

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