Perinatal outcomes in nulliparous women with a history of multiple pregnancy losses according to number of previous pregnancy losses

Peled, Tzuria; Nun, Eyal Lang Ben; Hochler, Hila; Sela, Hen Y.; Lipschuetz, Michal; Weiss, Ari; Grisaru‐Granovsky, Sorina; Rottenstreich, Misgav

doi:10.1016/j.ajogmf.2023.100946

American Journal of Obstetrics & Gynecology MFM

2023

DOI: 10.1016/j.ajogmf.2023.100946

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Perinatal outcomes in nulliparous women with a history of multiple pregnancy losses according to number of previous pregnancy losses

Tzuria Peled

Eyal Lang Ben Nun

Hila Hochler

et al.

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2024

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Cited by 4 publications

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Induction of labor in term pregnancies with isolated polyhydramnios: Is it beneficial or harmful?

Lerner,

Peled,

Priner Adler

et al. 2024

Intl J Gynecology & Obste

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ObjectiveTo compare rates of adverse pregnancy outcomes in term pregnancies complicated by polyhydramnios between women who had induction of labor (IOB) versus women who had expectant management.MethodsThis multicenter retrospective study included term pregnancies complicated by isolated polyhydramnios. Patients who underwent IOB were compared with those who had expectant management. The primary outcome was defined as a composite adverse maternal outcome, and secondary outcomes were various maternal and neonatal adverse outcomes. Univariate analyses were followed by multivariate logistic regression.ResultsA total of 865 pregnancies with term isolated polyhydramnios were included: 169 patients underwent IOB (19.5%), while 696 had expectant management and developed spontaneous onset of labor (80.5%). Women who underwent IOB had significantly higher rates of composite adverse maternal outcome (23.1% vs 9.8%, P < 0.01), prolonged hospital stay, perineal tear grade 3/4, intrapartum cesarean, postpartum hemorrhage, blood products transfusion, and neonatal asphyxia compared with expectant management. While the perinatal fetal death rate was similar between the groups (0.6% vs 0.6%, P = 0.98), the timing of the loss was different. Four women in the expectant management group had a stillbirth, while in the induction group one case of intrapartum fetal death occurred due to uterine rupture. Multivariate analyses revealed that IOB was associated with a higher rate of composite adverse maternal outcome (adjusted odds ratio, 2.22 [95% CI, 1.28–3.83]; P < 0.01).ConclusionIOB in women with term isolated polyhydramnios is associated with higher rates of adverse maternal outcomes in comparison to expectant management. Further research is needed to determine the optimal approach for the management of isolated polyhydramnios at term.

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Induction of labor in term pregnancies with isolated polyhydramnios: Is it beneficial or harmful?

Lerner,

Peled,

Priner Adler

et al. 2024

Intl J Gynecology & Obste

View full text Add to dashboard Cite

show abstract

Obstetric and perinatal outcomes of women with a history of recurrent pregnancy loss: a meta-analysis of cohort studies

Liu,

Zhao,

Zhuan

et al. 2024

Arch Gynecol Obstet

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Impact of first-trimester mechanical cervical dilatation during curettage on maternal and neonatal outcomes: A retrospective comparative study

Margaliot Kalifa,

Srebnik,

Sela

et al. 2024

European Journal of Obstetrics & Gynecology and Reproductiv

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Perinatal outcomes in nulliparous women with a history of multiple pregnancy losses according to number of previous pregnancy losses

Cited by 4 publications

References 22 publications

Induction of labor in term pregnancies with isolated polyhydramnios: Is it beneficial or harmful?

Induction of labor in term pregnancies with isolated polyhydramnios: Is it beneficial or harmful?

Obstetric and perinatal outcomes of women with a history of recurrent pregnancy loss: a meta-analysis of cohort studies

Impact of first-trimester mechanical cervical dilatation during curettage on maternal and neonatal outcomes: A retrospective comparative study

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