Perinatal outcome following induction of labor in patients with good glycemic controlled gestational diabetes: does timing matter?

Hochberg, Alyssa; Pardo, Anat; Oron, Galia; Krispin, Eyal; Amikam, Uri; Wiznitzer, Arnon; Hadar, Eran; Salman, Lina

doi:10.1007/s00404-019-05183-z

Cited by 8 publications

(8 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In this study, there was no statistical significance between medical history in the studied cases and the development of RDS in delivered infants; these results agree with the results cited by Hochberg et al [12] that support the link between pre-eclampsia in moms and preterm newborns with broncho-pulmonary dysplasia suggesting that chronic hypertension is protective for preterm neonates [13] . In contrast to our study, Li et al [14] concluded that maternal diabetes, including gestational diabetes mellitus and pregestational diabetes mellitus is connected to a higher incidence of neonatal RDS.…”

Section: Discussionsupporting

confidence: 91%

Prediction of Fetal Lung Maturity by Fetal Pulmonary Artery Doppler in Cases of Severe Pre-Eclampsia

Alkashty

Omar

Eid

2021

International Journal of Medical Arts

View full text Add to dashboard Cite

Background: Severe pre-eclampsia occurring remote from the term is a decision-making dilemma for the obstetrician, the general recommendation is that women with severe pre-eclampsia should be delivered to avoid maternal complications; others recommend prolonging pregnancy in most cases of severely premature pre-eclamptic gestation until the development of fetal lung maturity, development of fetal or maternal distress, or achievement of gestational age of 34 to 36-week of gestation. The cut-off level of pulmonary artery acceleration time to ejection time ratio [PAT/ET] that determines fetal lung maturity in cases of severe pre-eclampsia [PE] is not determined yet. Aim of the work:To study the Doppler indices of the main fetal pulmonary artery and their role in predicting respiratory distress syndrome [RDS] in severe pre-eclampsia.Patients and Methods: A prospective longitudinal cohort research was designed in which 102 pregnant women with PE were chosen and fetal pulmonary artery flow velocity data were acquired by Doppler ultrasound and linked with the development of neonatal RDS. Results:The AT/ET ratio in the fetal pulmonary artery velocity waveform was found to be directly related to the development of newborn RDS. A cut-off value of 0.3 resulted in a sensitivity of 71.4%, specificity of 79.7%, and total accuracy of 77.5%. Conclusion:A high AT/ET ratio in the fetal pulmonary artery is related to the future development of RDS in neonates of mothers with severe pre-eclampsia, implying that fetal pulmonary artery Doppler ultrasound may be a valuable tool in the identification of fetal lung maturity in situations of severe pre-eclampsia.

show abstract

Section: Discussionsupporting

confidence: 91%

Prediction of Fetal Lung Maturity by Fetal Pulmonary Artery Doppler in Cases of Severe Pre-Eclampsia

Alkashty

Omar

Eid

2021

International Journal of Medical Arts

View full text Add to dashboard Cite

show abstract

“…Nine studies in relation to diabetes were included, consisting of two Cochrane reviews [9,145], a secondary analysis of a trial that compared different treatments for mild gestational diabetes mellitus (GDM) [146] and six retrospective cohort studies [147][148][149][150][151][152]. With the exception of one study [145], all evaluated women with GDM, and excluded those with type I or II diabetes.…”

Section: Diabetesmentioning

confidence: 99%

“…Four studies assessed the impact of different timings of IOL for women with GDM in terms of CS rates [146,148] or maternal and neonatal outcomes [151,152]. A retrospective cohort study by Hochberg et al (2019) compared outcomes for IOL at 37+0 and 38 + 6 weeks (n = 193) versus 39+0 and 40+6 weeks (n = 237) and found that the rates of composite maternal outcome and composite neonatal outcome did not differ between groups [152]. A retrospective cohort study by Vitner et al (2019) found that IOL was associated with increased risk for adverse composite neonatal outcome or NICU admission when done prior to 39 weeks [151].…”

Section: Diabetesmentioning

confidence: 99%

A systematic scoping review of clinical indications for induction of labour

Coates¹,

Makris²,

Catling³

et al. 2020

PLoS ONE

View full text Add to dashboard Cite

Background The proportion of women undergoing induction of labour (IOL) has risen in recent decades, with significant variation within countries and between hospitals. The aim of this study was to review research supporting indications for IOL and determine which indications are supported by evidence and where knowledge gaps exist. Methods A systematic scoping review of quantitative studies of common indications for IOL. For each indication, we included systematic reviews/meta-analyses, randomised controlled trials (RCTs), cohort studies and case control studies that compared maternal and neonatal outcomes for different modes or timing of birth. Studies were identified via the databases PubMed, Maternity and Infant Care, CINAHL, EMBASE, and ClinicalTrials.gov from between April 2008 and November 2019, and also from reference lists of included studies. We identified 2554 abstracts and reviewed 300 full text articles. The quality of included studies was assessed using the RoB 2.0, the ROBINS-I and the ROBIN tool. Results 68 studies were included which related to post-term pregnancy (15), hypertension/preeclampsia (15), diabetes (9), prelabour rupture of membranes (5), twin pregnancy (5), suspected fetal compromise (4), maternal elevated body mass index (BMI) (4), intrahepatic cholestasis of pregnancy (3), suspected macrosomia (3), fetal gastroschisis (2), maternal age (2), and maternal cardiac disease (1). Available evidence supports IOL for women with post-term pregnancy, although the evidence is weak regarding the timing (41 versus 42

show abstract

“…This scheme was customized to account for glycemic control and fetal growth [21,22]. Well-controlled GD was diagnosed when 80% or more glucose measurements were within the range, estimated fetal weight was appropriate for gestational age, and the amniotic fluid index was normal, Fetal Diagn Ther 2022;49:77-84 DOI: 10.1159/000522203 regardless of treatment [23]. Women tested negative for the glucose tolerance test were considered nondiabetic (non-GD).…”

Section: Assessment Of Maternal and Fetal Characteristics And Ultraso...mentioning

confidence: 99%

Altered Doppler Velocimetry of Fetal Middle Cerebral Artery in Singleton Pregnancies Complicated by Mild Well-Controlled Gestational Diabetes

et al. 2022

View full text Add to dashboard Cite

Introduction The aim the present study is to evaluate fetal umbilical artery (UA) and middle cerebral artery (MCA) blood flow in patients with gestational diabetes (GD), in order to determine whether minimal anomalies of glucose metabolism may influence fetal placental function. Methods UA and MCA flow were prospectively measured by transabdominal ultrasound in singleton pregnancies between 34 and 37 weeks of gestation. Results The study included 35 women with GD and 217 non-diabetic patients. Middle cerebral pusatility index (PI) was significantly higher in the GD group (mean MCA – PI =1.82±0.27 vs 1.71 ±0.26; p< 0.02). Likewise, MCA peak systolic velocity (MCA-PSV) was higher in the GD group compared to the non-GD group, though the difference was not significant (mean of MCA-PSV =47.14 ±8.45 vs 47.09 ± 11.21; p = 0.98). UA-PI resulted higher in the non-GD group without significant differences (mean of UA-PI =0.88 ±0.14 vs 0.86 ± 0.15; p = 0.32) Conclusions Our study shows that even in cases of minimal metabolic derangements, GD is characterised by a significant variation in fetal Doppler velocimetry, particularly in the brain.

show abstract

Perinatal outcome following induction of labor in patients with good glycemic controlled gestational diabetes: does timing matter?

Cited by 8 publications

References 17 publications

Prediction of Fetal Lung Maturity by Fetal Pulmonary Artery Doppler in Cases of Severe Pre-Eclampsia

Prediction of Fetal Lung Maturity by Fetal Pulmonary Artery Doppler in Cases of Severe Pre-Eclampsia

A systematic scoping review of clinical indications for induction of labour

Altered Doppler Velocimetry of Fetal Middle Cerebral Artery in Singleton Pregnancies Complicated by Mild Well-Controlled Gestational Diabetes

Contact Info

Product

Resources

About