Perinatal Outcome after Cocaine ± Polydrug Exposure

Greene, Oliver; Varghese, Achamma; Tuamokumo, F.; Ashe, Warren K.; Ting, Pauline C.

doi:10.1111/j.1749-6632.1998.tb09764.x

Cited by 2 publications

(2 citation statements)

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“…Physical growth. Investigations of cocaine exposure on fetal physical development have consistently reported intrauterine growth retardation; specifically, retardation in length (height), weight, and head circumference (Cherukuri et al, 1988;Dow-Edwards, 1991;Lester et al, 1991;Little et al, 1989bLittle et al, , 1991Little and Snell, 1991b;Chasnoff, 1992;Coles et al, 1992;Schutter and Brinker, 1992;Mayes and Cichetti, 1995;Greene et al, 1998). Unfortunately, most studies reported birth status and little data are available regarding postnatal growth of children exposed prenatally to cocaine.…”

Section: Discussionmentioning

confidence: 99%

“…Several published studies and reports in the popular press suggest that in utero cocaine exposure is associated with atypical neurobehavioral development and prenatal growth retardation (Little, 1991;Little and Snell 1991a,b;Azuma and Chasnoff, 1993;Frank et al, 1993;Brooks-Gunn et al, 1994;Jacobson et al, 1996;Greene et al, 1998). Research indicates that cocaine remains an illegal drug frequently used by women of childbearing age (Schutter and Brinker, 1992;Scherling, 1994) and the incidence of cocaine usage may even be increasing.…”

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confidence: 99%

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Effects of prenatal cocaine exposure and postnatal environment on child development

2000

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Studies on the long‐term developmental effects of in utero cocaine exposure are few and the small number of studies published do not consider the postnatal environment. The present investigation was conducted to quantify the role that postnatal environment played compared to prenatal exposure. Four groups of 25 infants, each assessed at 12 months of age, were included in the study design: 1) noncocaine‐exposed children residing with their biological parents in low socioeconomic environments, 2) cocaine‐exposed children living with their biological parents in low socioeconomic environments, 3) noncocaine‐exposed children adopted at birth in middle to upper‐middle socioeconomic environments, and 4) cocaine‐exposed children adopted at birth. Infants were assessed by the Uzgiris‐Hunt Ordinal Scales of Infant Psychological Development, the Fagan Test of Infant Intelligence, and the Infant Monitoring Questionnaire. Height and head circumference were measured. Gender and ethnicity were controlled statistically. Significant differences were found in cognitive functioning, in fine motor development, and in physical growth between control and prenatally cocaine‐exposed children. Adoption enhanced cognitive functioning and fine motor skills among infants not exposed to cocaine prenatally, but had no apparent effect on infants prenatally exposed to cocaine. Am. J. Hum. Biol. 12:417–428, 2000. © 2000 Wiley‐Liss, Inc.

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