Perinatal nutritional intervention

Campoy, Cristina; Escudero-Marín, Mireia; Diéguez, Estefanía; Cerdó, Tomás

doi:10.1016/b978-0-12-813862-5.00008-6

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Epigenetic Effects Of Supplements In Pregnancy1

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2022

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“…Furthermore, GM generates folate and B vitamins that donate methyl groups for DNA or histone methylation. In this context, probiotics and prebiotics supplementation before pregnancy can induce an epigenetic effect on the host due to increased B and D vitamins and zinc status, thus improving maternal glycemia and glucose supply to the fetus-placental unit as well as promoting growth and optimal body composition of the offspring [74]. Morovic et al [75] defined epigenetics as "A New Frontier in Probiotic Research", distinguishing "epigenetics within an organisms opposed to the influence that an organism may have on the epigenetics of different organisms ('para-epigenetics')".…”

Section: Epigenetic Effects Of Supplements In Pregnancymentioning

confidence: 99%

Inositols, Probiotics, and Gestational Diabetes: Clinical and Epigenetic Aspects

et al. 2022

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There is growing interest in the potential role of different stereoisomers of inositol or their combination as well as probiotics supplementation in healthy glucose metabolism during pregnancy and in promoting offspring health. The aim of this review is to clarify the effects of several inositol and probiotics-based supplements in the prevention and treatment of gestational diabetes (GDM). Moreover, we will discuss the epigenetic aspects and their short- and long-term effects in response to probiotic intervention as well as the possible implications of these findings in guiding appropriate supplementation regimens in pregnancy.

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Section: Epigenetic Effects Of Supplements In Pregnancymentioning

confidence: 99%