Perinatal factors influencing the neonatal hearing screening results

Abstract

Background Previous studies have indicated that the majority of cases with “failed” results related to transient evoked otoacoustic emissions (OAE) test have the normal hearing. The present study aimed to assess the possible relationships between perinatal factors and the false-positive OAE results. Methods A case-control study was carried out in an Iranian Hospital in 2020. Based on the OAE results on the first day of life, newborns were divided into 2 groups; Control group included subjects with “Pass” OAE results. Every neonate with “Fail” OAE result was referred for auditory brainstem response (ABR). Neonates with bilateral fail OAE but normal ABR results (false-positive OAE) were considered as the case group. All recorded data were analyzed to assess the possible correlations between maternal/neonatal factors and the false-positive OAE results. Results One hundred and eighty-one neonates entered the study. Of all included neonates, 87 (48.1%) cases showed bilateral fail OAE and 94 (51.9%) subjects passed the OAE test. Normal ABR results (false-positive OAE) were observed in all cases with bilateral fail OAE. Comparisons of variables affecting the OAE results showed that of all perinatal factors, neonate’s sex (p = 0.046) and cesarean section (p = 0.003) were the only influencing factors that increased the risk of false-positive OAE results. Conclusion Based on the results, the cesarean section delivery and neonate’s male sex increased the risk of false-positive results related to OAE test. Implementing other screening tests such as ABR or Automated ABR as the initial screening test could be suggested for such cases.

Gentamicina no neonato: efeitos precoces e tardios sobre a audição

“…justificativas para esse dado foram levantadas, sendo a principal delas o fato deste grupo ser formado pelos neonatos com mais comorbidades associadas, necessitando de tempo de internação prolongada e ficando, portanto, expostos a vários IRDA, inclusive o uso de gentamicina e outras drogas ototóxicas associadas. Outros fatores que podem justificar esse alto índice de falha na triagem auditiva desse grupo são: excesso de ruído ambiental, uma vez que o serviço não dispõe de sala com tratamento acústico e ausência de reteste com PEATE, por falta do equipamento na maternidade Kaveh et al (2021),. encontraram um índice de falha (48,1%) na EOA similar ao do presente estudo.…”