Perinatal dioxin exposure and later effects––a review

Tusscher, G.W. ten; Koppe, Janna G.

doi:10.1016/s0045-6535(03)00254-6

Cited by 51 publications

(22 citation statements)

References 33 publications

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“…In terms of both pg/L and TEQ results, the CREs are all >99% for FC and PAC and 97-98% for AS. Compared to the results reported by Kim et al of 93% and 87% for treatment of whole drinking water [2], the CREs of the three coagulants were satisfactory during coagulation experiments. However, the sum of PCDD/Fs in SPM and TW (SPM + TW, Table 1) accounts for 80-85% of the PCDD/Fs in RW, leaving approximately 15-20% of PCDD/Fs not detected.…”

Section: Comparison Of Coagulation Efficiencycontrasting

confidence: 65%

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Removal of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans by three coagulants in simulated coagulation processes for drinking water treatment

Peng

Zhang

et al. 2009

Journal of Hazardous Materials

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Section: Comparison Of Coagulation Efficiencycontrasting

confidence: 65%

“…Polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) are toxic, chemically stable and present in almost all environmental compartments [1,2], which may pose serious adverse effects on human health and ecosystems. PCDD/Fs in water body may occur on suspended particles by sorption or in water by desolvation.…”

Section: Introductionmentioning

confidence: 99%

Removal of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans by three coagulants in simulated coagulation processes for drinking water treatment

Peng

Zhang

et al. 2009

Journal of Hazardous Materials

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“…The reader interested by all problems associated with human effects from occupational and epidemiological studies of dioxins may find necessary details in the following works: WHO (1997), CDC (1998), IOM (2001, ten Tusscher and Koppe (2004).…”

Section: Toxic Effects Of Dioxinmentioning

confidence: 99%

Levels and congener distributions of PCDDs, PCDFs and dioxin-like PCBs in environmental and human samples: a review

Srogi

2007

Environ Chem Lett

176

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The term ''dioxins'' is often used in a confusing way. In toxicological considerations-and also in the present report-the term is used to designate the PCDDs, the PCDFs and the coplanar (''dioxin-like'') PCBs, since these classes of compounds show the same type of toxicity. Because of the large number of congeners, relevant individual congeners are assigned with a toxic equivalency factor (TEF) that relate their toxicity to that of tetrachlorodibenzo-p-dioxin (TCDD) (2,3,7,8-TCDD) and are to be evaluated as dioxins. Each concentration of an individual congener in a mixture is multiplied with its TEF, and the resulting TCDD equivalents are added up and expressed as WHO-endorsed toxic equivalents (WHO-TEQ). Polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) are mainly the by-products of industrial processes (such as metallurgical processing, bleaching of paper pulp, and the manufacturing of some herbicides and pesticides) but they can also result from natural processes like volcanic eruptions and forest fires. Waste incineration, particularly if combustion is incomplete, is among the largest contributors to the release of PCDDs and PCDFs into the environment. Due to their persistence, PCDDs, PCDFs and PCBs are part of the socalled persistent organic pollutants group of compounds that also include some chlorinated pesticides. Since they have a high lipophilicity and resist transformation, they bio-accumulate in animal and human adipose tissues. Consumption of food is considered as the major source of non-occupational human exposure to PCDD/Fs with foodstuffs from animal origin accounting for more than 90% of the human body burden. With meat, dairy, and fish products being the main contributors. The aim of the present review was to summarize experimental data regarding dioxin emissions from contaminated and uncontaminated biological and environmental samples, from the available literature. The information will be presented chronologically with respect to distribution in human milk, serum; food, water, air, soils and sediments.

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“…Studies in rats and in mice have found TCDD to be a potent embryo/fetal toxin, developmental and teratogenic agent (Birnbaum, 1995;Peterson et al, 1993;ten Tusscher and Koppe, 2004). For example, in rats an in utero exposure to less than 1 g/kg TCDD results in a significant number of reproductive abnormalities including disruption of brain sexual differentiation and an increase incidence of cleft phallus, a persistent thread of tissue across the vaginal opening (Gray et al, 1997;Ikeda et al, 2005;Mably et al, 1992a,b,c).…”

Section: Introductionmentioning

confidence: 99%

Comparative developmental toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in the hamster, rat and guinea pig

2007

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Perinatal dioxin exposure and later effects––a review

Cited by 51 publications

References 33 publications

Removal of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans by three coagulants in simulated coagulation processes for drinking water treatment

Removal of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans by three coagulants in simulated coagulation processes for drinking water treatment

Levels and congener distributions of PCDDs, PCDFs and dioxin-like PCBs in environmental and human samples: a review

Comparative developmental toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in the hamster, rat and guinea pig

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