Perinatal and Infant Mortality in Term and Preterm Births Among Women With Type 1 Diabetes

Eidem, Ingvild; Vangen, Siri; Hanssen, Kristian F.; Vollset, Stein Emil; Henriksen, Tore; Joner, Geir; Stene, Lars C.

doi:10.1097/ogx.0b013e31824b6f5f

Cited by 24 publications

(40 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…[19] [14]. Four studies from the UK reported strikingly similar results, possibly reflecting the increased homogeneity of care [15][16][17][18].…”

Section: Discussionsupporting

confidence: 59%

“…Eidem et al [14] and dos Santos Silva et al [15] examined whether the RR of stillbirth associated with diabetes varied by gestational age, both reporting that the effect was confined to term deliveries. In contrast, we found the RR of stillbirth was uniformly raised for all gestational ages.…”

Section: Discussionmentioning

confidence: 99%

“…It is uncertain, however, whether such improvements can be achieved in routine clinical care. Observational studies from the last 20 years have not shown any reduction in the RR of fetal death [9][10][11][12][13][14][15][16][17][18], despite guidelines advising women with pre-existing diabetes to achieve good glycaemic control before pregnancy [19,20].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Pre-existing diabetes, maternal glycated haemoglobin, and the risks of fetal and infant death: a population-based study

et al. 2013

View full text Add to dashboard Cite

Aims/hypothesis Pre-existing diabetes is associated with an increased risk of stillbirth, but few studies have excluded the effect of congenital anomalies. This study used data from a long-standing population-based survey of women with preexisting diabetes to investigate the risks of fetal and infant death and quantify the contribution of glycaemic control. Methods All normally formed singleton offspring of women with pre-existing diabetes (1,206 with type 1 diabetes and 342 with type 2 diabetes) in the North of England during 1996-2008 were identified from the Northern Diabetes in Pregnancy Survey. RRs of fetal death (≥20 weeks of gestation) and infant death were estimated by comparison with population data from the Northern Perinatal Morbidity and Mortality Survey. Predictors of fetal and infant death in women with pre-existing diabetes were examined by logistic regression. Results The prevalence of fetal death in women with diabetes was over four times greater than in those without (RR 4 Conclusions/interpretation Pre-existing diabetes is associated with a substantially increased risk of fetal and infant death in normally formed offspring, the effect of which is largely moderated by glycaemic control.

show abstract

“…[19] [14]. Four studies from the UK reported strikingly similar results, possibly reflecting the increased homogeneity of care [15][16][17][18].…”

Section: Discussionsupporting

confidence: 59%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Pre-existing diabetes, maternal glycated haemoglobin, and the risks of fetal and infant death: a population-based study

et al. 2013

View full text Add to dashboard Cite

show abstract

“…The cohort represents a quite homogenous population of almost exclusively ethnic Norwegians with good access to a public healthcare system [26,28]. The main limitation of our study is that we did not have information on the causes of death or clinical data from the subjects such as HbA 1c .…”

Section: Discussionmentioning

confidence: 99%

All-cause mortality in a nationwide cohort of childhood-onset diabetes in Norway 1973–2013

et al. 2015

View full text Add to dashboard Cite

Aims/hypothesis The aim of this study was to assess the association between all-cause mortality and sex, age at diagnosis and year of diagnosis in Norwegian patients with childhoodonset diabetes. Methods The study was based on the nationwide, populationbased Norwegian Childhood Diabetes Registry, which includes all newly diagnosed cases of childhood-onset diabetes at age 0-14 years in 1973-1982 and 1989-2012 (n=7,884). Patients were followed until date of death, emigration or 30 September 2013. Results Among the 7,884 patients, representing 132,420 person-years, 249 (3.2%) died during a mean follow-up of 16.8 (range 0.0-40.7) years. The standardised mortality ratio (SMR) for the total cohort was 3.6 (95% CI 3.1, 4.0), increasing by attained age. Absolute mortality was significantly lower in females than in males (HR 0.50 [95% CI 0.38, 0.65]), although the SMRs were similar. Cox regression analysis showed a significant decrease in mortality of 49% (HR 0.51 [95% CI 0.28, 0.93]) for those diagnosed in 1999-2012 compared with those diagnosed in 1973-1982 (p=0.03). Conclusions/interpretation In spite of improved diabetes care, mortality is still three to four times higher in those with childhood-onset diabetes compared with the general population in Norway. However, absolute mortality has declined among children diagnosed most recently (1999)(2000)(2001)(2002)(2003)(2004)(2005)(2006)(2007)(2008)(2009)(2010)(2011)(2012) compared with those diagnosed in the earliest period (1973)(1974)(1975)(1976)(1977)(1978)(1979)(1980)(1981)(1982).

show abstract

“…72 Pregnant women with diabetes mellitus and CHD Women with diabetes mellitus have considerably higher risks of adverse pregnancy outcomes, including birth defects, than nondiabetic women. 73 And pregestational maternal diabetes mellitus is the only relatively prevalent population risk factor for congenital heart defects (CHDs). 18 Even though the association of pregestational diabetes mellitus with CHD has been known for decades, it is not clear if this knowledge has resulted in a substantive impact of the reduction of pregnancies complicated by diabetes mellitus or in the proportion of births with CHDs attributable to pregestational diabetes mellitus.…”

Section: Maternal Use Of Bupropionmentioning

confidence: 99%

Noninherited Risk Factors of Congenital Heart Defects in Offspring: A Revi

Mamun

Hussain

Hasan

et al. 2017

Bangladesh J Child Health

View full text Add to dashboard Cite

show abstract

Perinatal and Infant Mortality in Term and Preterm Births Among Women With Type 1 Diabetes

Cited by 24 publications

References 0 publications

Pre-existing diabetes, maternal glycated haemoglobin, and the risks of fetal and infant death: a population-based study

Pre-existing diabetes, maternal glycated haemoglobin, and the risks of fetal and infant death: a population-based study

All-cause mortality in a nationwide cohort of childhood-onset diabetes in Norway 1973–2013

Noninherited Risk Factors of Congenital Heart Defects in Offspring: A Revi

Contact Info

Product

Resources

About