Perilaku Merokok  di Masa Covid-19

Ruhyat, Ejeb

doi:10.38037/jsm.v15i1.178

Cited by 5 publications

(3 citation statements)

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“…Data provided by WHO in 2018 (WHO, 2019) and Riskesdas in 2018 (Kementrian RI, 2018) revealed that 70.7% and 62.9% of males in Indonesia were active smokers. The nicotine concentration in cigarettes activates ACE-2 receptors on the lung's respiratory epithelium and endothelial cells, thereby increasing access to SARS-CoV-2 and making it bind to the receptors (Ruhyat, 2021).…”

Section: Discussionmentioning

confidence: 99%

Effect of fondaparinux anticoagulants on D-dimer levels in Covid-19 patients

Putra,

A.N.T,

Suprapti

et al. 2023

Pharm Educ

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Background: Anticoagulants can prevent thromboembolic activities, improve prognosis, and reduce the mortality rate in Covid-19 patients with coagulopathy. Objective: To analyse the effect of Fondaparinux in decreasing D-dimer levels, and to determine the correlation between patient characteristics, disease severity, and D-dimer levels. Methods: This is a single-centre retrospective cohort study using the medical records of Covid-19 in-patients who were ≥ 17 years old, on Fondaparinux 2.5 mg OD and had D-dimer measurement pre-and post-five days-Fondaparinux therapy during hospitalisation at referral general hospital in Bengkulu, Indonesia between April 2020 and December 2021. The data were assessed to evaluate the differences in the pre-post D-dimer levels, the relationship between patient characteristics and disease severity, and the relationship between disease severity and D-dimer levels. Results: A total of thirty-six patients were included in this study, of which 52.78% were males and 44.44% were aged 46-55 years old. Furthermore, 88.89% had comorbidity, and 55.55% had moderate severity. There was a significant decrease in D-dimer levels in all disease severity (p < 0.05). Patient characteristics and disease severity were not associated with D-dimer depletion (p > 0.05). Conclusion: Fondaparinux reduced the D-dimer levels in all severity of Covid-19 patients.

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Section: Discussionmentioning

confidence: 99%

Effect of fondaparinux anticoagulants on D-dimer levels in Covid-19 patients

Putra,

A.N.T,

Suprapti

et al. 2023

Pharm Educ

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“…Pengaktifan reseptor ACE2 ini akan memfasilitasi SARS-CoV-2 untuk masuk dan berikatan dengan reseptor ACE2 pada sel epitel dan endotel saluran pernapasan. Hal inilah yang mengakibatkan laki-laki yang merokok lebih rentan terinfeksi COVID-19 dibandingkan perempuan yang tidak merokok (Ruhyat, 2021). Merokok juga dapat menyebabkan keadaan prokoagulan, peradangan, peningkatan kadar fibrinogen plasma, peningkatan faktor VIII, berkurang proses fibrinolisis dan peningkatan kekentalan darah yang dapat berkembang menjadi VTE (Tromboemboli Vena).…”

Section: Rsud Dr M Yunusunclassified

Profil Penggunaan Antikoagulan Pada Pasien Covid-19 Di Irna Fatmawati Rsud DR M Yunus Bengkulu

Putra¹,

Suprapti²,

Sari³

et al. 2022

jmk

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Permasalahan: COVID-19 merupakan penyakit infeksi saluran pernapasan yang dapat menular pada manusia dan disebabkan oleh SARS-CoV-2. COVID-19 telah menyebar secara global hingga tanggal 25 Januari 2022 total kasus konfirmasi COVID-19 di dunia berjumlah 355.682.845 kasus dengan angka kematian sebesar 5.623.412 (CFR 1,6%) yang terjadi di 225 negara. Sedangkan di Indonesia sendiri terdapat 4.289.305 orang yang terkonfirmasi COVID-19 dengan angka kematian sebesar 144.227 (CFR 3,4%). Komplikasi yang menyertai COVID-19 adalah terjadinya koagulopati, untuk itu antikoagulan merupakan salah satu obat yang digunakan dalam penanganan COVID-19. Namun, pencatatan penggunaan antikoagulan pada pasien COVID-19 yang diselenggarakan oleh Badan Penelitian dan Pengembangan Kesehatan di Indonesia masih kurang lengkap. Tujuan penelitian: Untuk mengetahui profil penggunaan antikoagulan pasien COVID-19 yang dirawat di IRNA Fatmawati RSUD Dr M Yunus Bengkulu. Metode penelitian: Penelitian ini merupakan penelitian observasional deskriptif dengan pengambilan data secara retrospektif menggunakan teknik time limited sampling, dimana data berasal dari rekam medis pasien COVID-19 yang dirawat di IRNA Fatmawati RSUD Dr M Yunus Bengkulu dan memenuhi kriteria inklusi pada periode April 2020–Desember 2021. Hasil: Pada penelitian ini diperoleh 258 rekam medis pasien COVID-19 yang memenuhi kriteria inklusi, dengan proporsi lebih besar pada jenis kelamin laki-laki (58,1%) dibanding perempuan (41,9%). Penggunaan antikoagulan terbesar pada usia 56-65 tahun mencapai 37,6%. Fondaparinuks merupakan antikoagulan yang paling banyak digunakan (51,2%) diikuti dengan antikoagulan heparin (36,8%) dan enoksaparin (12,1%). Kesimpulan: Laki-laki dengan usia 56-65 tahun lebih berisiko terinfeksi COVID-19 dan komplikasi koagulopati sehingga membutuhkan penggunaan antikoagulan. Fondaparinuks paling banyak digunakan pada penelitian ini untuk mencegah kejadian tromboemboli dan meningkatkan prognosis pasien COVID-19 dengan koagulopati.

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“…During lockdown restrictions, nicotine use increased in five countries: Italy, India, South Africa, the United States, and the United Kingdom, including Indonesia (Ruhyat, 2021;Yach, 2020). Indonesia remains the first country for male smokers globally (Holipah et al, 2020).…”

Section: Introductionmentioning

confidence: 99%

Food and cigarettes expenses during COVID-19 pandemic on diet quality in Jakarta and surroundings

2023

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It is clearly understood that the economic disruption during the COVID-19 outbreak is causing people to lose their income and access to healthy food. Our study aims to investigate people's spending on food and how their daily expenses on cigarettes impact diet quality. We conducted a cross-sectional online survey in April, 2020 and interviews through social media. There were 180 subjects followed in this study. Analysis was conducted using chi-square. It is found that even though our subjects able to access food but their diet quality to have whole food of four food group daily is not adequate. There is significant association between food expenses on whole food and processed food to diet quality (p<0,001). While there is no significant association between smoking behaviours to diet quality (p=0,684) but the percentage of those who smoke 1 to 3 cigarettes and more than 3 cigarettes daily is larger to have poor diet quality rather than people who do not smoke at all. This study concluded household's expenses for cigarettes and food during the COVID-19 pandemic were able to explain whether diet quality is poor or good. The study suggests the government needs to impose smoking restrictions as part of COVID-19 prevention and reassure people's accessibility to nutritious food during this pandemic.

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Perilaku Merokok di Masa Covid-19

Cited by 5 publications

References 0 publications

Effect of fondaparinux anticoagulants on D-dimer levels in Covid-19 patients

Effect of fondaparinux anticoagulants on D-dimer levels in Covid-19 patients

Profil Penggunaan Antikoagulan Pada Pasien Covid-19 Di Irna Fatmawati Rsud DR M Yunus Bengkulu

Food and cigarettes expenses during COVID-19 pandemic on diet quality in Jakarta and surroundings

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