Periimplantitis and Implant Body Roughness

Jordana, Fabienne; Susbielles, Léa; Colat-Parros, Jacques

doi:10.1097/id.0000000000000834

Cited by 27 publications

(20 citation statements)

References 56 publications

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“…Ag- 4,23 It can enter the bacteria body, interfere with DNA replication, disturb activity of metabolic enzymes, suppress cell proliferation, and eventually lead to bacterial death. [24][25][26][27] The excellent short-term antibacterial ability of Ag-containing titanium coatings is also well documented by other reports. 3,4,6,14,23 Titanium implants are durable prosthesis and will exist in oral cavity for many years, [28][29][30] during which they will inevitably face dental plaque colonization and bacteria-induced periimplantitis.…”

Section: Discussionsupporting

confidence: 66%

“…Ag + shows high antibacterial activity and can kill both gram‐positive and gram‐negative bacteria 4,23 . It can enter the bacteria body, interfere with DNA replication, disturb activity of metabolic enzymes, suppress cell proliferation, and eventually lead to bacterial death 24‐27 . The excellent short‐term antibacterial ability of Ag‐containing titanium coatings is also well documented by other reports 3,4,6,14,23 …”

Section: Discussionmentioning

confidence: 78%

“…Ag is the strongest element against microbes 3,4,6,14,23,24,26 and it can kill bacteria either in its ion form or by a mechanism of contactkilling. 28,30,32 Direct contact of Ag with bacteria will cause destruction of cell wall and plasma membrane, leading to leakage of intracellular substances and eventually bacteria lysis.…”

Section: Discussionmentioning

confidence: 99%

“…Cell proliferation were also significantly inhibited in group Sr/Ag0. 34 Osteogenic potential is another pursue to improve implant biological property, not only for early implant osseointegration, but also for their long-term use, because implants will inevitably face bacteria infection during their lifespan 26,30,34 and require reosseointegation after successful treatment of infection. 7,33 Sr can stimulate proliferation and differentiation of osteoblasts, suppress differentiation and activity of osteoclasts, 16,35 and therefore facilitate bone growth by promoting new bone formation and inhibiting bone resorption.…”

Section: Discussionmentioning

confidence: 99%

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Evaluation of osteogenic and antibacterial properties of strontium/silver‐containing porous TiO₂ coatings prepared by micro‐arc oxidation

Zhang

Zhu

et al. 2020

J Biomed Mater Res

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Ti and Ti alloys are bioinert materials and two frequent problems associated with them are bacterial infection and lack of osteogenic potential for rapid bone integration. To overcome the problems, the present study incorporated strontium (Sr) and silver (Ag) simultaneously into porous TiO2 coatings through a single‐step technique, micro‐arc oxidation (MAO). Incorporation of Sr and Ag brought no significant changes to coating micromorphology and physicochemical properties, but endowed TiO2 coatings with both strong antibacterial activity and osteogenic ability. Antibacterial activity increased with Ag contents in the coatings. When Ag content reached 0.58 wt%, the coating showed both excellent short‐term (100.0%) and long‐term (77.6%) antibacterial activities. Sr/Ag‐containing coatings with 18.23 wt% Sr and 0.58 wt% Ag also presented good cytocompatibility for preosteoblast adhesion and proliferation, and promoted preosteoblast osteogenic differentiation both short‐termly and long‐termly. However, higher Ag content (1.29 wt%) showed toxic effects to preosteoblasts. In summary, MAO is a simple and effective way to incorporate Sr and Ag into porous TiO2 coatings and Sr/Ag‐containing TiO2 coating with 18.5 wt% Sr and 0.58 wt% Ag has both good osteogenic activity and strong antibacterial capability short‐termly and long‐termly. Therefore, such coatings are valuable for clinical application to strengthen osseointegration and long‐term high quality use of titanum implants.

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Section: Discussionsupporting

confidence: 66%

Section: Discussionmentioning

confidence: 78%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Evaluation of osteogenic and antibacterial properties of strontium/silver‐containing porous TiO₂ coatings prepared by micro‐arc oxidation

Zhang

Zhu

et al. 2020

J Biomed Mater Res

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“…7,[13][14][15][16][17] However, the high roughness of SLM implants has been found to promote dental plaque accumulation and increase the risk of inflammation and bone loss in dental implant sites. [18][19][20] Thus, surface modification of SLM implants is necessary for improving long-term clinical outcome.…”

Section: Introductionmentioning

confidence: 99%

Surface modification of titanium manufactured through selective laser melting inhibited osteoclast differentiation through mitogen-activated protein kinase signaling pathway

Yang

Zhang

et al. 2020

J Biomater Appl

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Selective laser melting used in manufacturing custom-made titanium implants becomes more popular. In view of the important role played by osteoclasts in peri-implant bone resorption and osseointegration, we modified selective laser melting-manufactured titanium surfaces using sandblasting/alkali-heating and sandblasting/acid-etching, and investigated their effect on osteoclast differentiation as well as their underlying mechanisms. The properties of the surfaces, including elements, roughness, wettability and topography, were analyzed. We evaluated the proliferation and morphology of primary mouse bone marrow-derived monocytes, as well as induced osteoclasts derived from bone marrow-derived monocytes, on samples. Then, osteoclast differentiation was determined by the tartrate-resistant acid phosphatase activity assay, calcitonin receptors immunofluorescence staining and the expression of osteoclast-related genes. The results showed that sandblasting/alkali-heating established nanonet structure with the lowest water contact angle, and both sandblasting/alkali-heating and sandblasting/acid-etching significantly decreased surface roughness and heterogeneity compared with selective laser melting. Surface modifications of selective laser melting-produced titanium altered bone marrow-derived monocyte morphology and suppressed bone marrow-derived monocyte proliferation and osteoclastogenesis in vitro (sandblasting/alkali-heating>sandblasting/acid-etching>selective laser melting). These surface modifications reduced the activation of extracellular signal-regulated kinase and c-Jun N-terminal kinases compared to native-selective laser melting. Sandblasting/alkali-heating additionally blocked tumor necrosis factor receptor-associated factor 6 recruitment. The results suggested that sandblasting/alkali-heating and sandblasting/acid-etching modifications on selective laser melting titanium could inhibit osteoclast differentiation through suppressing extracellular signal-regulated kinase and c-Jun N-terminal kinase phosphorylation in mitogen-activated protein kinase signaling pathway and provide a promising technique which might reduce peri-implant bone resorption for optimizing native-selective laser melting implants.

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Cytocompatibility, antibacterial, and corrosion properties of chitosan/polymethacrylates and chitosan/poly(4‐vinylpyridine) smart coatings, electrophoretically deposited on nanosilver‐decorated titania nanotubes

Pawłowski,

Bartmański,

Ronowska

et al. 2023

J Biomed Mater Res

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The development of novel implants subjected to surface modification to achieve high osteointegration properties at simultaneous antimicrobial activity is a highly current problem. This study involved different surface treatments of titanium surface, mainly by electrochemical oxidation to produce a nanotubular oxide layer (TNTs), a subsequent electrochemical reduction of silver nitrate and decoration of a nanotubular surface with silver nanoparticles (AgNPs), and finally electrophoretic deposition (EPD) of a composite of chitosan (CS) and either polymethacrylate‐based copolymer Eudragit E 100 (EE100) or poly(4‐vinylpyridine) (P4VP) coating. The effects of each stage of this multi‐step modification were examined in terms of morphology, roughness, wettability, corrosion resistance, coating‐substrate adhesion, antibacterial properties, and osteoblast cell adhesion and proliferation. The results showed that the titanium surface formed nanotubes (inner diameter of 97 ± 12 nm, length of 342 ± 36 nm) subsequently covered with silver nanoparticles (with a diameter of 88 ± 8 nm). Further, the silver‐decorated nanotubes were tightly coated with biopolymer films. Most of the applied modifications increased both the roughness and the surface contact angle of the samples. The deposition of biopolymer coatings resulted in reduced burst release of silver. The coated samples revealed potent antimicrobial activity against both Gram‐positive and Gram‐negative bacteria. Total elimination (99.9%) of E. coli was recorded for a sample with CS/P4VP coating. Cytotoxicity results using hFOB 1.19, a human osteoblast cell line, showed that after 3 days the tested modifications did not affect the cellular growth according to the titanium control. The proposed innovative multilayer antibacterial coatings can be successful for titanium implants as effective postoperative anti‐inflammation protection.

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Periimplantitis and Implant Body Roughness

Cited by 27 publications

References 56 publications

Evaluation of osteogenic and antibacterial properties of strontium/silver‐containing porous TiO₂ coatings prepared by micro‐arc oxidation

Evaluation of osteogenic and antibacterial properties of strontium/silver‐containing porous TiO₂ coatings prepared by micro‐arc oxidation

Surface modification of titanium manufactured through selective laser melting inhibited osteoclast differentiation through mitogen-activated protein kinase signaling pathway

Cytocompatibility, antibacterial, and corrosion properties of chitosan/polymethacrylates and chitosan/poly(4‐vinylpyridine) smart coatings, electrophoretically deposited on nanosilver‐decorated titania nanotubes

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Periimplantitis and Implant Body Roughness

Cited by 27 publications

References 56 publications

Evaluation of osteogenic and antibacterial properties of strontium/silver‐containing porous TiO2 coatings prepared by micro‐arc oxidation

Evaluation of osteogenic and antibacterial properties of strontium/silver‐containing porous TiO2 coatings prepared by micro‐arc oxidation

Surface modification of titanium manufactured through selective laser melting inhibited osteoclast differentiation through mitogen-activated protein kinase signaling pathway

Cytocompatibility, antibacterial, and corrosion properties of chitosan/polymethacrylates and chitosan/poly(4‐vinylpyridine) smart coatings, electrophoretically deposited on nanosilver‐decorated titania nanotubes

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Evaluation of osteogenic and antibacterial properties of strontium/silver‐containing porous TiO₂ coatings prepared by micro‐arc oxidation

Evaluation of osteogenic and antibacterial properties of strontium/silver‐containing porous TiO₂ coatings prepared by micro‐arc oxidation