Perigraft seroma with minute observations after Gore-Tex graft implantation

Ando, Takashi; Morito, Haruna; Okada, Hiroshi; Furukawa, Hiroshi

doi:10.1177/0218492314533975

Cited by 1 publication

(1 citation statement)

References 4 publications

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“…Local haemostatic agents such as Bioglue were utilized in all aortic dissection cases, which may also have contributed to PGS formation. Aortic wall inflammation and fibrin leakage from the polytetrafluoroethylene (PTFE) graft have been reported to cause PGS [ 9 ]. Warfarin use has been a known risk factor for PGS formation [ 4 ].…”

Section: Discussionmentioning

confidence: 99%

Mediastinal perigraft seroma after thoracic aortic surgery

Suzuki,

Akita,

Miyazaki

et al. 2023

Interdisciplinary CardioVascular and Thoracic Surgery

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OBJECTIVES We investigated pertinent factors associated with mediastinal perigraft seroma (PGS) after thoracic aortic surgery. In addition, we provided a clinical review of this entity, as reports reviewing abundant mediastinal PGS cases are rare. METHODS Eighty-two patients who underwent either ascending aortic replacement or aortic arch replacement between 2016 and 2022 in our institution were enrolled in the present study. Postoperative computed tomography scans were performed to detect fluid capsules with a diameter ≥3.0 cm and radiodensity ≤25 Hounsfield units. Patients who did and who did not develop PGS formation were compared. Variables with a statistically significant difference between these groups were included in a multiple logistic regression analysis along with other factors associated with PGS in the literature. RESULTS The incidence rate of PGS was 14.6% (12/82). The average radiodensity of the mass was 16.6 ± 6.3 Hounsfield units. The average onset of PGS was 8.5 months post-surgery. Multivariate logistic regression analysis revealed that ejection fraction [odds ratio (OR): 1.25, 95% confidence interval (CI): 1.03–1.50, P = 0.021], aortic dissection (versus degenerative aortic aneurysm) (OR: 6.61, 95% CI: 1.35–32.4, P = 0.02) and warfarin use (OR: 6.67, 95% CI: 1.19–37.1, P = 0.03) significantly contributed to mediastinal PGS after thoracic aortic surgery. CONCLUSIONS High ejection fraction, warfarin use and aortic dissection (versus degenerative aortic aneurysm) contributed significantly to mediastinal PGS formation after thoracic aortic surgery. Careful serial postoperative imaging studies and fluid analysis can be used to guide treatment plans. Clinical trial registration UMIN-CTR (University hospital Medical Information Network-Clinical Trial Registry) Registration number: UMIN000050764.

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Section: Discussionmentioning

confidence: 99%