Perifollicular vascularity as a potential variable affecting outcome in stimulated intrauterine insemination treatment cycles: a study using transvaginal power Doppler

Abstract

These data would suggest that perifollicular vascularity has an important role to play in the outcome of IUI cycles, and that power Doppler has the potential to refine the management of assisted reproduction treatment cycles.

Follicle and corpus luteum size and vascularity as predictors of fertility at the time of artificial insemination and embryo transfer in beef cattle

“…Previous studies also assessed these parameters in cattle (Siddiqui et al 2008. ), horses (Silva et al 2006), and humans (Coulam et al 1999, Bhal et al 2001, Borini et al 2001, and encountered a positive correlation between FL vascularity and fertility. In the present study, CL vascularity was positive related with pregnancy rate at the time of embryo transfer, but no relationship with fertility was noted when follicle size and vascularity were measured at the time of AI.…”

“…Therefore, since it is a non invasive technique and with reliable application, it is a useful tool to target new reproductive diagnoses. The evaluation of perifollicular vascularity was done in cows (Siddiqui et al 2008), women (Coulam et al 1999, Bhal et al 2001, Borini et al 2001, and mares (Silva et al 2006), and in all of these species was detected greater vascularity in the preovulatory follicle wall in individuals that became pregnant after mating.…”

Relationship of vascular perfusion of the wall of the preovulatory follicle to in vitro fertilisation and embryo development in heifers

“…In women, several studies have indicated that the blood flow in the wall of the preovulatory follicle is an indication of the potential success of assisted reproductive techniques. Preovulatory examination of colour Doppler signals of blood flow in the follicular wall (Bhal et al 2001) and vascular resistance distal to an intraovarian artery by spectral Doppler indices (Du et al 2006) are useful for assessing the quality of the oocyte. Bhal et al (2001) reported that follicle vascularity is a factor in determining the success of pregnancy establishment after intrauterine insemination.…”

“…Preovulatory examination of colour Doppler signals of blood flow in the follicular wall (Bhal et al 2001) and vascular resistance distal to an intraovarian artery by spectral Doppler indices (Du et al 2006) are useful for assessing the quality of the oocyte. Bhal et al (2001) reported that follicle vascularity is a factor in determining the success of pregnancy establishment after intrauterine insemination. Greater blood flow in the wall of the preovulatory follicle also has been associated with improved rates of in vitro fertilisation (IVF) and embryo development (Bhal et al 1999, Coulam et al 1999, Huey et al 1999, Du et al 2006, Shrestha et al 2006.…”

“…In summary, greater vascularity of the preovulatory follicle has been associated with greater follicular diameter (women: Bhal et al 1999, mares: Silva et al 2006, heifers: Siddiqui et al 2009b, retrieval rate of oocytes (women: Bhal et al 1999, mares: Ginther et al 2007, retrieval rate of mature oocytes (mares: Ginther et al 2007, Siddiqui et al 2009a, fertilisation rate (women: Bhal et al 1999Bhal et al , 2001) and pregnancy rate (women: Bhal et al 1999, Coulam et al 1999, Huey et al 1999, Du et al 2006, Shrestha et al 2006, mares: Silva et al 2006, heifers: Siddiqui et al 2009b, and lower incidence of triploidy (women: Bhal et al 2001). Studies on the relationship between blood-flow characteristics of the wall of the preovulatory follicle to oocyte retrieval and maturity have been done only in women and mares, and studies on fertilisation and embryo development of the oocyte after IVF have been done only in women.…”