Perifollicular Fibromas

Zackheim, Herschel S.

doi:10.1001/archderm.1960.01580060067008

Cited by 71 publications

(30 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Perifollicular fibromas [1] are characterized by concentric proliferation of connective tissue surround ing small follicles; fibrofolliculomas [4,10] have a double component: epithelial strands in an anastomosizing pattern, located in the upper part of the follicle, above the level of the sebaceous gland, and loose connective tissue with abundant mucopolysaccharides surrounding the epithelial component with resemblance to fibroadenoma of the breast on low-power examination; trichodiscomas [2] arc composed of a highly vascular con nective tissue with abundant mucosubstances.…”

Section: Commentmentioning

confidence: 99%

“…They arc commonly distributed over the face, neck and shoulders, or cover ing wide areas of the skin. In 1960, Zackheim and Pinkns [1] first proposed the exis tence of tumors derived from the fibrous root sheath, and they introduced the term 'peri follicular fibromas' to describe benign fibro mas with perifollicular arrangement of the collagen fibers. In 1974, Pinkns ct al.…”

mentioning

confidence: 99%

See 1 more Smart Citation

Multiple Fibrofolliculomas and Trichodiscomas

Moreno¹,

Puig

Moragas

1985

Dermatology

View full text Add to dashboard Cite

A late-onset, sporadic case of multiple fibrofolliculomas and trichodiscomas is reported. This case and other reports in the literature suggest to the authors that benign neoplasms derived from the mesodermal component of the pilar apparatus may present in various combinations and may also be associated with other hamartomatous skin proliferations. The wide spectrum of published combinations may be due to similarities in clinical presentation and biopsy-sampling uncertainties

show abstract

Section: Commentmentioning

confidence: 99%

mentioning

confidence: 99%

Multiple Fibrofolliculomas and Trichodiscomas

Moreno¹,

Puig

Moragas

1985

Dermatology

View full text Add to dashboard Cite

show abstract

“…It presents usually as a single small, firm, skin-coloured papule and is often misdiagnosed as melanocytic naevus, wart or small nodular basal cell carcinoma. The origin of the FPF has been debated and it has been considered to be a perifollicular fibroma [1], a resolving melanocytic naevus [2], an angiofibroma [3] or a proliferative reactive process consisting mainly of dermal dendrocytes [4]. …”

Section: Introductionmentioning

confidence: 99%

Fibrous Papule of the Face with Granular Cells

2007

View full text Add to dashboard Cite

Fibrous papule of the face is a common benign lesion located most often on the nose. It presents usually as a single small, firm, skin-coloured papule and is often misdiagnosed as melanocytic naevus, wart or small nodular basal cell carcinoma. Histopathologically, the lesions are characterized by involvement of the upper dermis by a fibrovascular proliferation and scattered triangular or stellate, often multinucleated cells. Uncommon histopathologic variants of fibrous papule of the face include hypercellular, clear-cell, pleomorphic, pigmented, inflammatory and granular-cell types. We present here a patient with the syndrome of familial cancer and fibrous papule of the face with granular cells. The granules stained strongly with PAS stain, as well as with CD68 and NKI/C3 immunostains, whereas S-100 protein resulted negative. In our patient the mutations in the 2 most often affected DNA mismatch repair genes of Muir-Torre syndrome were not found, therefore the origin of the familial cancer syndrome remains unknown. Probably the occurrence of the granular-cell fibrous papule of the face was coincidental.

show abstract

“…It can occur as a solitary papule or as multiple lesions 2 . Multiple PFF lesions have been linked to adenomatous colonic polyps and they may be inherited as an autosomal dominant trait 3 .…”

Section: Introductionmentioning

confidence: 99%