Pericyte in retinal vascular diseases: A multifunctional regulator and potential therapeutic target
Quan Zhang,
Xianchun Yan,
Hua Han
et al.
Abstract:Retinal vascular diseases (RVDs), in particular diabetic retinopathy, retinal vein occlusion, and retinopathy of prematurity, are leading contributors to blindness. The pathogenesis of RVD involves vessel dilatation, leakage, and occlusion; however, the specific underlying mechanisms remain unclear. Recent findings have indicated that pericytes (PCs), as critical members of the vascular mural cells, significantly contribute to the progression of RVDs, including detachment from microvessels, alteration of contr… Show more
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