Pericarditis and Auricular Fibrillation

Gale, A. E.; Levin, Marvin E.

doi:10.1001/archinte.1963.03860020132018

Cited by 16 publications

(1 citation statement)

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“…Prolonged inflammation in FMF, particularly untreated or refractory cases, appears to develop amyloidosis. This may contribute to atrial fibrosis and degradation of atrial conduction time and refractory duration of atrial myocardium [7][8][9]. Atrial arrhythmias can be caused by electromechanical and electrophysiological anomalies of the atrium, such as increased atrial electromechanical delay (AED) and increased P-wave dispersion (Pdisp) [10].…”

Section: Introductionmentioning

confidence: 99%

Ailevi Akdeniz Ateşi tanılı çocuklarda gecikmiş atrial ileti zamanı

Battal

Binnetoğlu

Aylanç

et al. 2021

Family Practice and Palliative Care

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Introduction: Familial Mediterranean Fever (FMF) is a disease with recurrent fever, characterized by painful, noninfectious inflammation of the serous membranes. It mostly affects Armenians, Turks, Arabs and Jews. Prolonged inflammation in FMF may lead to atrial fibrosis which can cause the deterioration of atrial conduction time and refractory periods of atrial myocardium.In the present study we aimed to assess atrial conduction time in children with FMF. Methods: The study included 36, children diagnosed with FMF(17 males/19 females, 13 (7-15) years) and 20 control(7 males/13 females, 11 (9-16) years) cases in our Pediatric Outpatient Clinic between October 2015 and October 2016. Tissue Doppler Echocardiography (TDE) measurements of intra-and interatrial electromechanical delay were done. P wave dispersion (Pdisp) was calculated from the 12-lead electrocardiogram. Results: Inter-atrial (Lateral PA-Tricuspid PA) and Intra-left (Lateral PA-Septal PA) atrial electromechanical delay were significantly longer in FMF patients (P<0.001,respectively). (PA: the time range between the beginning of the P wave in the surface electrocardiogram and the beginning of the tissue Doppler late diastolic wave A). Also, P-wave dispersion (Pdisp) were significantly higher in FMF patients ( p= 0.002). Conclusions: This study shows that atrial electromechanical delay and Pdisp are prolonged in children with FMF. We recommend that atrial conduction time be measured for children diagnosed with FMF.

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