Pericardiectomy for treatment of neoplastic constrictive pericarditis

Büyükbayrak, Fuat; Aksoy, Eray; Dedemoğlu, Mehmet; Kırali, Kaan; Mete, Hızır

doi:10.1177/0218492313484317

Cited by 9 publications

(11 citation statements)

References 15 publications

(15 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The severity of malignant pericardial effusion is evident with low survival reported by many authors. Studies with cancer patients and PE report median survival ranging from 112 days to 5 months . Our median survival was 43 days, lower than previously reported, but some characteristics of our patients could explain this finding.…”

Section: Discussioncontrasting

confidence: 86%

“…It was observed in 7% of our cases. Previous papers have conflicting results regarding its etiology, physiopathology, and incidence, with the latter varying from 5% to as high as 87.5% . This large difference might be a result of varied criteria to its occurrence.…”

Section: Discussionmentioning

confidence: 98%

“…Malignant pericardial effusion is most frequently caused by lung and breast cancers, lymphomas, leukemias, tumors of the esophagus and melanoma . The effusion may result from the direct extension, metastatic spread, infection, or from complications associated with chemo‐radiotherapy …”

Section: Introductionmentioning

confidence: 99%

“…The standard treatment for PE is surgical drainage or pericardiocentesis. The last, however, has recurrence rates as high as 90% in 90 days . Considering the poor prognosis among these patients, it is fundamental to identify who might benefit from surgical drainage, by achieving stability and getting discharged from the hospital, in opposition to futile or even harmful anesthetic and surgical risks.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Predictors of hospital discharge in cancer patients with pericardial effusion undergoing surgical pericardial drainage

Kazantzis

Bibas

Dela-Vega

et al. 2018

Journal of Surgical Oncology

View full text Add to dashboard Cite

Introduction Pericardial effusion (PE) is a complication of late‐stage cancer and some patients never leave the hospital despite drainage. The main objective of this study was to identify predictors of hospital discharge in cancer patients with (PE) who underwent pericardial drainage. We also report the occurrence of paradoxical hemodynamic instability (PHI). Methods and Materials A retrospective study was carried out in a cancer center. Patients included had malignancy, PE, and underwent surgical drainage. An institutional database was reviewed for preoperative variables, analyzed for hospital discharge. Results One‐hundred and thirteen patients were included, with a mean age of 54 years old (SD 14.3). Sixty‐three patients were discharged from hospital (55.7%). Age (odds ratio [OR], 1.04; P = 0.004), higher ECOG status (OR, 0.63; P = 0.019), recent chemotherapy (OR, 3.40; P = 0.007), and renal failure (OR, 0.14; P = 0.002) were associated with hospital discharge. Median survival was 43 days (IQ 25%‐75%; 15‐162). Patients with pulmonary embolism or neutropenia were at greater risk of developing PHI (OR, 10.11; P = 0.009 and OR, 12.13; P = 0.015, respectively). Conclusion Almost half of the patients never left the hospital. Patients with no chemotherapy within 45 days of procedure, patients with renal failure and higher ECOG status are at greater risk of not getting discharged. PHI remains a serious condition with high mortality.

show abstract

Section: Discussioncontrasting

confidence: 86%

Section: Discussionmentioning

confidence: 98%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Predictors of hospital discharge in cancer patients with pericardial effusion undergoing surgical pericardial drainage

Kazantzis

Bibas

Dela-Vega

et al. 2018

Journal of Surgical Oncology

View full text Add to dashboard Cite

show abstract

“…External beam radiotherapy may have a role in very selected cases, as tumor encasement of the heart or extensive pericardial infiltration by non-resectable tumors and, with modern radiation therapy techniques, as intensity modulated radiation therapy, the radiation beam can be focused over the neoplastic mass reducing the burden over the cardiovascular structures (FIGURE 5). Surgery, in these cases, has a very high perioperative mortality and morbidity [72].…”

Section: Antineoplastic Treatmentsmentioning

confidence: 99%

2015 update on the diagnosis and management of neoplastic pericardial disease

Lestuzzi

Berretta

Tomkowski³

2015

Expert Review of Cardiovascular Therapy

View full text Add to dashboard Cite

The best approach in diagnosis and treatment of neoplastic pericardial disease has not been defined yet. The authors report the most recent literature about the new diagnostic techniques that are useful to improve the diagnosis. The literature about the therapeutic options is critically reviewed, in order to give suggestions of use to the clinical practice. Pericardial effusion may require urgent drainage; the solid component, however, becomes predominant in some cases. Neoplastic pericardial disease should be assessed following oncologic criteria evaluation of the neoplastic burden; outcome classified as complete or partial response, stable or progressive disease and - in cases with progression - event-free survival. Systemic chemotherapy may be effective in lymphomas and possibly in breast carcinomas. Intrapericardial chemotherapy with systemic chemotherapy is the treatment of choice in lung cancer. Pericardial window with systemic chemotherapy is also effective in preventing the accumulation of large amount of fluid.

show abstract

Massive pericardial effusion as the first manifestation of childhood non‐Hodgkin's lymphoma: A case report

Alizadeh

Shaye

Badiea

et al. 2021

Clinical Case Reports

View full text Add to dashboard Cite

show abstract

Pericardiectomy for treatment of neoplastic constrictive pericarditis

Abstract: Pericardial constriction may develop a long time after the initial presentation of certain neoplastic diseases, and the prognosis after pericardiectomy is poor.

Cited by 9 publications

References 15 publications

Predictors of hospital discharge in cancer patients with pericardial effusion undergoing surgical pericardial drainage

Predictors of hospital discharge in cancer patients with pericardial effusion undergoing surgical pericardial drainage

2015 update on the diagnosis and management of neoplastic pericardial disease

Massive pericardial effusion as the first manifestation of childhood non‐Hodgkin's lymphoma: A case report

Contact Info

Product

Resources

About