Periarteritis Nodosa

McBride and the midfacial granuloma syndrome

“…Such complications may arise many years after the primary lesion and diagnosis. Nieberding et al (1963) have described a borderline form of Wegener's granulomatosis with extensive necrosis of the nose and midline tissues. These authors also support the concept of a spectrum of intermediate types.…”

McBride and the midfacial granuloma syndrome

“…Stewart's type, the systemic and the limited form of Wegener's granulomatosis, can best be regarded as 'variants of a single disorder probably vascular in its basis and possibly due to a disturbance that is immunologically determined' (Friedmann and Osborn, 1976). Such an approach 'appears to be more useful and productive than repeated attempts at subdivision and the creation of newer and confusing clinical entities' (Nieberding et al, 1963).…”