Peri-ureteric mass an unusual case of immunoglobin G4-related disease (IgG4-RD)

Abstract

Immunoglobulin G4-related disease (IgG4-RD) of the ureter is a rarely reported disease, often mimicking urothelial carcinoma. This paper describes a case of an otherwise healthy patient with a lesion involving the ureter revealed on Computed tomography (CT), avid on fludeoxyglucose positron emission tomography (FDG PET), that prior to surgery was suspicious for urothelial carcinoma, until intra-op frozen section revealed otherwise. Diagnosis of ureteral IgG4-RD should be considered as a differential diagnosis, with serum IgG4 levels obtained.

Ureter Metastasis From Colorectal Cancer Revealed on 18F-FDG PET/CT

“…18 F-FDG PET/CT has been proven to be useful in detecting the recurrence and distant metastasis of malignant neoplasm. 3,[11][12][13][14] Various etiologies of increased 18 F-FDG uptake have also been well described, including urothelial carcinoma, 15 primary small cell carcinoma, 3 carcinoma of the ureteral stump, 16 IgG4-related disease, 17 and chronic granulomatous disease. 18 The current case indicates metastatic ureteral cancer must be considered in the differential diagnosis.…”