“…As very few regenerative life support systems have yet been implemented operationally on-orbit for water, better confidence/bounds on crew water use for long duration missions are even more critical, considering only moderate levels of closure may exist for early missions to the Moon and Mars. Past spaceflight experience and ground based studies can provide results useful for future water use estimates (Colombo et al, 1971;NASA, 1970;Verostko et al, 1997;Philistine, 2005;Osburg, 2007). The value of results increases when conducting a monitoring program under operationally relevant mission constraints and in an operationally relevant environment.…”