Performance of the Mood Disorder Questionnaire (MDQ) according to bipolar subtype and symptom severity

Abstract

Despite some fluctuations over time and a discrete influence of symptom severity, the screening algorithm can be used reliably, whether in the acute or remission phase of a depressive episode.

Screening for Bipolar Disorder with the Mood Disorders Questionnaire: A Review

“…33,37,44,46,48 The results were similar to the previous comparison of scoring algorithms, though the differences were not as great. That is, compared to the results based on the Hirschfeld cutoff, the broader definition of a case improved the MDQ's sensitivity by 13.7%, reduced its specificity by 3.3%, had no impact on its positive predictive value, and slightly increased its negative predictive value.…”

“…[28][29][30]32,33,37,[39][40][41]45,46,48 In 2 studies bipolar II disorder was defined more broadly than how the disorder is defined in DSM-IV, with a minimum-duration requirement of two days rather than DSM-IV's minimum of four days. 28,30 The data in Table 4 show that in each of the 12 studies, the MDQ's sensitivity was higher in detecting bipolar I disorder than bipolar II disorder.…”

Validation of the Chinese version of the "Mood Disorder Questionnaire" for screening bipolar disorder among patients with a current depressive episode

“…Although the originator of the MDQ did not specially access patients in remission from a mood episode, whether the patient's symptomatology at the time of screening will affect the MDQ performance is an interesting topic. A previous study with a small sample size [24] showed the performance of MDQ was independent of depressive symptoms, but the relatively low test-retest reliability(kappa coefficient 0.64) with the whole sample implicated the possible influence of clinically relevant factors, such as the patient's mood state at time of completion. While compared to a report which sampled patients treated for depression [15], the performance of the MDQ in detecting BPDII in this study was quite close (sensibility: 0.706 vs. 0.70), in spite of the different cut-off (7 vs. 4).…”

Screening for bipolar disorder in adolescents with the Mood Disorder Questionnaire – Adolescent version (MDQ‐A) and the Child Bipolar Questionnaire (CBQ)

“…This value was nevertheless comparable with the one of the adult MDQ in general psychiatric outpatient services. 53 Test-retest reliability was not addressed in the original MDQ-A study, 47 whereas it was 0.81 for the CBQ over an average much shorter 3-day time interval. 46 In summary, the present study with adolescents contrasts with early studies using the MDQ in adults with mood disorders 50,55 and the MDQ-A or CBQ parent reports in adolescents, 47,52 which documented good predictive performances in detecting BD.…”