Performance of the Asthma Impact on Quality of Life Scale (A-IQOLS) in diverse asthma research populations and demographic subgroups

Wilson, Sandra R.; Wise, Robert A.; Castro, Mario; Mulligan, Michael J.; Ayala, Estela; Chausow, Alan; Huang, Qiwen; Gummidipundi, Santosh

doi:10.1016/j.jaci.2018.02.056

Cited by 3 publications

(2 citation statements)

References 27 publications

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“…As the prevalence of asthma continues to increase across countries of all economic levels, this number is projected to increase to 400 million by 2025 [1]. Although there has been some decline in deaths and hospitalizations from asthma, partly through the increasing availability of effective medications [2], the condition can still have a dramatic and detrimental effect on quality of life (QoL) [3][4][5], and is thought to cause around 250,000 deaths annually [1].…”

Section: Introductionmentioning

confidence: 99%

Relationship between handheld and clinic-based spirometry measurements in asthma patients receiving beclomethasone

Kerwin

Hickey

Small

2019

Respiratory Medicine

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Introduction: Handheld spirometers for home use by patients allow longitudinal spirometry data to be collected daily and may overcome some of the limitations of in-clinic spirometry (long intervals between measurements, results can be affected by site-based coaching and patient's asthma status during a given visit). Objectives: To determine the relationship between spirometry values measured by clinic-based and handheld spirometers during a clinical trial. Methods: A post hoc correlation analysis of data from a 6-week phase 3 study of beclomethasone dipropionate (BDP; delivered by breath-actuated inhaler: BAI) versus placebo in patients aged ≥12 years with persistent asthma. During the study, forced expiratory volume in 1 s (FEV 1 ) was assessed by both office-based spirometry at Weeks 2, 4 and 6, and daily by handheld spirometer as a secondary study endpoint. Results: There was a high correlation between FEV 1 values measured at home and in-clinic (overall correlation coefficient = 0.8393, R = 0.81921, 0.85927, 0.85369 and 0.83734 for BAI 320 μg/day, BAI 640 μg/day, BDP metered dose inhaler 320 μg/day and placebo treatment groups, respectively), with the scatterplot showing an upward trend for all treatment groups. Nearly all patients achieved home FEV 1 values close to clinic FEV 1 values, with very few outliers. Conclusions: Clinic-based and handheld spirometry demonstrated comparable treatment effects relative to placebo, suggesting that home spirometry could be used to help patients monitor their asthma severity. Daily measurement of FEV 1 provides more comprehensive data than can be achieved through clinic visits, and may lead to a new approach to clinical trial design.

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Section: Introductionmentioning

confidence: 99%

Relationship between handheld and clinic-based spirometry measurements in asthma patients receiving beclomethasone

Kerwin

Hickey

Small

2019

Respiratory Medicine

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“…There's a lot of evidence that sexual dysfunctions can occur with chronic illness (1) . Asthma, a chronic disease causes physical, mental, social, and economic losses and thus affects the quality of life of individuals (2) . Also, quality of life decreases due to factors such as inability to perform activities of daily living, hospitalizations, long duration of treatment, and side effects of medication (3) .…”

Section: Introductionmentioning

confidence: 99%

Male Sexual Dysfunction Among Asthmatic Patients. A Cross Sectional Study

El-Sorougi,

Lawendy,

Soliman

et al. 2023

Ain Shams Medical Journal

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Background: Asthma affects 1-18% of the population in different countries. Its prevalence varies worldwide but more than 5% of any investigated population suffer from asthma. The effect of asthma on sexual function of these patients is still not clear. Aim of the Work: This work aims to assess the relation between asthma and erectile dysfunction, and if there is any relation between the degree of asthma severity and the severity of erectile dysfunction.Patients and Methods: Our study was conducted on two groups: Group A includes 120 male asthmatic patients who were enrolled consecutively from the patients attending outpatient clinics of Helwan University hospitals and Abassya Chest diseases Hospital and group B (the control group) including 100 healthy volunteers.Results: It was found that asthmatic patients included in the current study had lower International Index of Erectile Function 5 (IIEF-5) scores than the controls. Also, we found that most of cases of moderate asthma had mild erectile dysfunction (73.2%) and only 8.5% had mild to moderate erectile dysfunction. While most of those with severe asthma, 39.5% had mild ED and 31.6% had mild to moderate ED Conclusions: Patients with asthma have a higher prevalence of erectile dysfunction. Education level, occupational status, asthma duration, asthma severity and control level were independent risk factors for sexual dysfunction and poor quality of life. Therefore, to improve the quality of life, patients with asthma should be evaluated holistically, their sexual functions should be taken into account and multidisciplinary approaches should be applied.

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Relationship between health-related quality of life and subjective wellbeing in asthma

Albornoz

Chen

2021

Journal of Psychosomatic Research

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Performance of the Asthma Impact on Quality of Life Scale (A-IQOLS) in diverse asthma research populations and demographic subgroups

Abstract: A-IQOLS is valid for research and potentially clinical use in demographically and clinically diverse patients.

Cited by 3 publications

References 27 publications

Relationship between handheld and clinic-based spirometry measurements in asthma patients receiving beclomethasone

Relationship between handheld and clinic-based spirometry measurements in asthma patients receiving beclomethasone

Male Sexual Dysfunction Among Asthmatic Patients. A Cross Sectional Study

Relationship between health-related quality of life and subjective wellbeing in asthma

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