Performance of subjects with multiple sclerosis on tests of high-level language

Lethlean, Jennifer; Murdoch, Bruce E.

doi:10.1080/02687039708248454

Cited by 58 publications

(31 citation statements)

References 55 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The diversity of reports of language compromise in MS available to date may be largely representative of the variable nature of the disease course, and importantly the presence or absence of a cognitive decline. To the present day, revelations of language dysfunction in MS have been largely facilitated by the introduction of more sensitive assessment batteries targeting higher-order language behaviours (Lethlean & Murdoch, 1997;Murdoch & Lethlean, 2000) rather than the general language abilities which, previous studies have testified to be within normal limits in RR (Anzola et al, 1990) and CP (Mackenzie & Green, 2009) subtypes. Investigations affording behavioural evidence of language profiles in MS have been suitably complimented by the introduction of state-of-the-art neuroimaging techniques to assess and examine the integrity of white matter pathways influencing linguistic processing associated with the neuropathology (Sepulcre et al, 2011).…”

Section: Introductionmentioning

confidence: 99%

“…The most convincing evidence has been afforded via higher-level language outcome measures (Lethlean & Murdoch, 1994. Lethlean and Murdoch (1997) offer the most substantive group evidence available to date on the higher-level language characteristics of CP and RR subtype MS patients. These authors report a substantially reduced metalinguistic performance of both RR and CP subtypes as recorded on two standardised assessments.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Cognitive linguistic deficits in relapsing–remitting multiple sclerosis

Barwood

Murdoch

2013

Aphasiology

Self Cite

View full text Add to dashboard Cite

Background: Recent years have witnessed increasing reports of language dysfunction associated with the neuropathology of multiple sclerosis (MS). Although linguistic compromise is not traditionally thought to be a significant clinical manifestation of MS, a number of published case and group reports have uncovered the presence of higher-level language and isolated general language deficits in samples of patients with both chronic progressive and relapsing-remitting (RR) subtypes of the disease. To the present day however, the precise nature and extent of a language compromise in MS remains largely controversial and unclear. Aims: The present study aims to profile the cognitive linguistic abilities of a cohort of fifteen RR-subtype MS patients against an age-and education-matched group of neurologically normal control participants. Methods & Procedures: MS participants were assessed using a comprehensive battery of cognitive linguistic assessments targeting general and higher-level language behaviours. Outcomes & Results:The results revealed reduced performance on higher-level language subtests including: listening comprehension (making inferences), oral expression (recreating sentences), semantic absurdities and definitions. For the general language behaviours, a reduced performance was found for spontaneously elicited speech, repetition and naming. Conclusions: The findings are suggestive of both expressive language and higher-level language dysfunction in RR subtype MS and highlight deficits in linguistic organisation, retrieval mechanisms and semantic manipulation and processing.

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Cognitive linguistic deficits in relapsing–remitting multiple sclerosis

Barwood

Murdoch

2013

Aphasiology

Self Cite

View full text Add to dashboard Cite

show abstract

“…In other words, high-level/complex language makes more demands of one sort or another than, say, the simple language functions which are said to remain intact in the populations being investigated. Lethlean and Murdoch (1997) describe the tasks in their study of high level language in multiple sclerosis as those which 'entail the use of varied areas of language and extensive cognitive processing' (p. 47), while several studies of language in populations with subcortical lesions (e.g., Cook et al, 2004;Copland et al, 2000) refer to complex or high-level language measures as those which demand frontal lobe support in the manipulation of novel situations, lexical semantic operations, the development of language strategies, and the organisation and monitoring of responses. The manual for the Right Hemisphere Language Battery (Bryan, 1989) refers to 'noncomponential, nonliteral, more complex features of language which are context bound' (p. 5).…”

Section: High(er) Level/(more) Complex Languagementioning

confidence: 97%

“…Not surprisingly, this has produced something of an overabundance of potential terms. These include 'cognitive-language' (Hagen, 1982), 'cognitive-pragmatic' (McDonald, 1992a), 'high-level' (and indeed 'higher-level') language (Cook et al, 2004;Hinchliffe et al, 1998a;Laakso et al, 2000;Lethlean & Murdoch, 1997;Moran & Gillon, 2004), 'higher order' language (Hinchliffe et al, 1998a), 'complex' and 'more complex' language (Hinchliffe et al, 1998a;Wapner et al, 1981), 'pragmatic' (Channon & Watts, 2003;Martin & McDonald, 2003;Meilijson et al, 2004), 'cognitive-communicative' (and 'cognitive-communication';Chapman et al, 2004;MacDonald & Johnson, 2005;Sbordone, 1988;Turkstra et al, 2005) and 'cognitive-linguistic' (cognitive-language; Cherney, 1991;Ellmo et al, 1995;Hinchliffe et al, 1998b;Whelan & Murdoch, 2005).…”

Section: Terminologymentioning

confidence: 98%

Terminology and Methodology in the Assessment of Cognitive-Linguistic Disorders

Body¹,

Perkins

2006

Brain Impairment

View full text Add to dashboard Cite

The term ‘cognitive-linguistic’ has been widely adopted in descriptions of a variety of communication disorders of neurogenic origin. Despite this, clear agreement on the meaning of the term has yet to be reached, with the result that it is used both inconsistently and misleadingly. This lack of terminological clarity also undermines the assessment of complex communicative function. In this article the terminology associated with complex communication disorders is discussed and a simple framework for conceptualising cognitive-linguistic function is outlined. On the basis of this it is proposed that some currently available assessments that purport to measure cognitive-linguistic skills in fact have less explanatory power than other assessments that are often not specifically targeted at communication. Further, it is suggested that the framework offers an ecologically valid basis for the systematic assessment of cognitive-linguistic function.

show abstract

“…A second reason is that many lay people do not understand the difference between expressive language and speech [19]. Friend et al [20] and Lethlean and Murdoch [21] have provided new insights into and an awareness of the need to explore the high-level language disorders (subtle but important to the individual) frequently found in persons diagnosed with MS. Language difficulties -though not as profound as the cognitive problems, such as attention -may also be a symptom of MS, and thus, it is important to make this distinction.…”

mentioning

confidence: 99%

Perceptions of the Impact of Speech, Language, Swallowing, and Hearing Difficulties on Quality of Life of a Group of South African Persons with Multiple Sclerosis

Klugman

Ross

2002

Folia Phoniatr Logop

View full text Add to dashboard Cite

The present study investigated perceptions of speech, language, swallowing, and hearing difficulties and the relative impact of these problems on quality of life (QOL) in a group of South African persons with multiple sclerosis (MS). A questionnaire was used to elicit information regarding the difficulties experienced and the perceptions of their influence on QOL. Of the 30 respondents, 56.7% experienced speech problems and 63.3% reported language difficulties, with 62% of those feeling that these speech and language difficulties impacted on QOL. Fifty percent reported swallowing problems with 53% of those perceiving an influence on QOL. Twenty-three percent of participants experienced hearing problems with 44% expressing the view that their QOL was influenced. These findings are discussed with regard to their implications for the education and counselling of individuals with MS and their families, incorporation of speech-language pathologists and audiologists into management teams, and further research.

show abstract

Performance of subjects with multiple sclerosis on tests of high-level language

Cited by 58 publications

References 55 publications

Cognitive linguistic deficits in relapsing–remitting multiple sclerosis

Cognitive linguistic deficits in relapsing–remitting multiple sclerosis

Terminology and Methodology in the Assessment of Cognitive-Linguistic Disorders

Perceptions of the Impact of Speech, Language, Swallowing, and Hearing Difficulties on Quality of Life of a Group of South African Persons with Multiple Sclerosis

Contact Info

Product

Resources

About