Performance of nanoimprinted and nanocoated optical label-free biosensor - nanocoating properties perspective

Dziekan, Zofia; Pituła, Emil; Kwietniewski, Norbert; Stonio, Bartłomiej; Janik, Monika; Śmiarowski, Tomasz; Koba, Marcin; Parzuchowski, Paweł G.; Niedziółka‐Jönsson, Joanna; Śmietana, Mateusz

doi:10.1016/j.optlaseng.2022.107009

Cited by 5 publications

(5 citation statements)

References 40 publications

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“…The reason may be that the longer sensing length leads to larger phase differences resulting in shorter interference periods [30]. The simulation work results show good agreement with the relationship between the phase difference and the sensing length of the MZI, as shown in equation (2).…”

Section: The Simulation Resultssupporting

confidence: 73%

“…[1]. Integrated label-free optical sensors are a promising choice because they have many unique advantages in biochemical detection, including high refractive index (RI) sensitivity, wide dynamic range, low cost, as well as low detection limits [2,3]. In addition, they can be integrated with other micro-nano devices and placed in harsh environments.…”

Section: Introductionmentioning

confidence: 99%

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Refractive Index Sensing Performances of a Mid-Infrared Asymmetric Mzi Based on Suspended Gaas Waveguides

Wang¹,

Ma²,

Ma³

et al. 2022

PIER M

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A novel mid-infrared (MIR) biochemistry sensor using two suspended GaAs waveguides based on an asymmetric Mach-Zender Interferometer (MZI) is proposed. The propagation properties and refractive index (RI) sensing performances of MZI are investigated by the finite element method (FEM). The simulation results show that the maximum waveguide sensitivities (S wg ) of the TE and TM modes in the suspended GaAs waveguide are ∼ 1.2 and ∼ 1.0. This design of the GaAs waveguide using the suspension structure is to enhance the interaction between the vanishing field and measured material. The RI sensitivity of the asymmetric MZI structure increases with the length of the sensing arm, which can reach 854.5 nm/RIU with a Q of 208.2 after parameter optimization. The two arms of the MZI are designed as width-asymmetric structures to make the sensor more sensitive to the measured material. The asymmetric MZI sensing structure has high RI sensitivity and compact structure, which provides a feasible scheme for biochemical sensing.

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Section: The Simulation Resultssupporting

confidence: 73%

Section: Introductionmentioning

confidence: 99%

Refractive Index Sensing Performances of a Mid-Infrared Asymmetric Mzi Based on Suspended Gaas Waveguides

Wang¹,

Ma²,

Ma³

et al. 2022

PIER M

View full text Add to dashboard Cite

show abstract

“…In order to increase the sensibility of sensing materials, photonic crystals have been proposed as periodic arrangements of dielectric materials built in an area of incoming radiation [ 58 ]. Similar to the bandgap in semiconductors, they have a photonic bandgap where it is forbidden for some wavelengths to pass through their structure [ 59 ].…”

Section: Sars-cov-2 Biosensorsmentioning

confidence: 99%

A Framework for Biosensors Assisted by Multiphoton Effects and Machine Learning

et al. 2022

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The ability to interpret information through automatic sensors is one of the most important pillars of modern technology. In particular, the potential of biosensors has been used to evaluate biological information of living organisms, and to detect danger or predict urgent situations in a battlefield, as in the invasion of SARS-CoV-2 in this era. This work is devoted to describing a panoramic overview of optical biosensors that can be improved by the assistance of nonlinear optics and machine learning methods. Optical biosensors have demonstrated their effectiveness in detecting a diverse range of viruses. Specifically, the SARS-CoV-2 virus has generated disturbance all over the world, and biosensors have emerged as a key for providing an analysis based on physical and chemical phenomena. In this perspective, we highlight how multiphoton interactions can be responsible for an enhancement in sensibility exhibited by biosensors. The nonlinear optical effects open up a series of options to expand the applications of optical biosensors. Nonlinearities together with computer tools are suitable for the identification of complex low-dimensional agents. Machine learning methods can approximate functions to reveal patterns in the detection of dynamic objects in the human body and determine viruses, harmful entities, or strange kinetics in cells.

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“…Due to the ordered periodic structure of CCAs, iridescent structural colors emerge from Bragg reflection and constructive interference 10–13 . The iridescent structural colors make them promising for various applications, such as anti‐counterfeiting labels, 14−16 biosensors 17,18 and color displays and printing 19−22 . If the CCAs are integrated with hydrogel polymers, the structural colors are tunable upon hydrogel swelling or shrinking.…”

Section: Introductionmentioning

confidence: 99%

A selectivity‐enhanced colloidal crystal array for ribavirin sensing based on the synergistic effect of covalent and non‐covalent interactions

Chen

Sun

Zhang

et al. 2023

Polymer International

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Ribavirin is an important antiviral with demonstrated activity against coronaviruses such as severe acute respiratory syndrome coronavirus and coronavirus disease 2019 virus. However, abuse of ribavirin will cause great environmental damage and threaten human health owing to its reproductive toxicity and teratogenicity. Therefore, an innovative detection method is demanded for simple and sensitive detection of ribavirin. This work reports an imprinted colloidal crystal array (ICCA) for ribavirin sensing. The building blocks of the ICCA are ribavirin imprinted spheres, which possess superior binding efficiency toward ribavirin. Benefiting from the highly ordered structure, the ICCA exhibits optical properties which change upon binding ribavirin. The changes in reflectance wavelength enable a fast and label‐free detection of ribavirin between 21 and 245 μmol L−1. Moreover, the sensor shows excellent selectivity for ribavirin detection in river water. Overall, all the results reported in this work demonstrate that the ICCA should be a promising detection tool for antivirals. © 2023 Society of Industrial Chemistry.

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Performance of nanoimprinted and nanocoated optical label-free biosensor - nanocoating properties perspective

Cited by 5 publications

References 40 publications

Refractive Index Sensing Performances of a Mid-Infrared Asymmetric Mzi Based on Suspended Gaas Waveguides

Refractive Index Sensing Performances of a Mid-Infrared Asymmetric Mzi Based on Suspended Gaas Waveguides

A Framework for Biosensors Assisted by Multiphoton Effects and Machine Learning

A selectivity‐enhanced colloidal crystal array for ribavirin sensing based on the synergistic effect of covalent and non‐covalent interactions

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