“…The confirmation that stated dietary phytate inhibits sugar digestion and blood glucose in rats (Dilworth et al, 2004) and mice (Lee et al, 2006) resulted in this assumption that anti-nutritional factors capable of altering nutrient utilization might regulate associated gene expression (Liu et al, 2008b). Many studies have shown the effectiveness of phytase supplementation to improve the digestibility of phytate-bound P in poultry diets as well as reducing P excretion (Tangendjaja, Chung, & Broz, 2002) Several experiments have reported the efficacy of microbial phytase in laying hens and broilers diet (Mathlouthi, Larbier, Mohamed, & Lessire, 2002;Panda, Rao, Raju, & Bhanja, 2005;Cowieson & Ravindran, 2007;Liu et al, 2007;Liu et al, 2008a).…”