Performance of honed surface profiles to artificial hip joints: An experimental investigation

Choudhury, Dipankar; Walker, Robert; Roy, Taposh; Paul, Sweety; Mootanah, Rajshree

doi:10.1007/s12541-013-0247-z

Cited by 35 publications

(18 citation statements)

References 18 publications

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“…It confirms the better lubricating ability of the DLC-coated dimpled surface. It was reported in previous studies that a dimpled surface reduces the friction because it increases hydrodynamic pressure under sliding conditions [12, 36, 37]. Our study shows similar results.…”

Section: Resultssupporting

confidence: 91%

Tribological investigation of diamond-like carbon coated micro-dimpled surface under bovine serum and osteoarthritis oriented synovial fluid

Ghosh

Choudhury

Roy

et al. 2015

Science and Technology of Advanced Materials

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Osteoarthritis-oriented synovial fluid (OASF), i.e., that typical of a patient with osteoarthritis, has different physical and biological characteristics than bovine serum (BS), a lubricant widely used in biotribological investigations. Micro-dimpled and diamond-like carbon- (DLC) coated surfaces are key emerging interfaces for orthopedic implants. In this study, tribological performances of dimpled surfaces, with and without DLC coating, have been investigated under both BS and OASF. The friction tests were performed utilizing a pin on a disk tribometer, whereas contact pressure, speed, and temperature were simulated to a ‘medium walking gait’ of hip joint conditions. The mechanical properties of the specimen and the physical properties of the lubricant were characterized before the friction test. Raman analysis was conducted to identify the coating condition both before and after the test. The DLC-coated dimpled surface showed maximum hardness and residual stress. A DLC-coated dimpled surface under an OASF lubricated condition yielded a lower friction coefficient and wear compared to those of plain and dimpled specimens. The higher graphitization of coated materials with increasing load was confirmed by Raman spectroscopy.

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Section: Resultssupporting

confidence: 91%

Tribological investigation of diamond-like carbon coated micro-dimpled surface under bovine serum and osteoarthritis oriented synovial fluid

Ghosh

Choudhury

Roy

et al. 2015

Science and Technology of Advanced Materials

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“…Generally, because the synovial fluid in the joint cavity of the normal human body has high viscosity, the microscaffolds cannot freely move by a high fluid drag force in the normal synovial fluid . However, in the damaged joint, it is reported that the viscosity of the synovial fluid decreases to the range of 20–30 cP by an inflammatory reaction around the cartilage defects . Thus, we adopted a glycerin (70% (v/v)) solution at room temperature (25–26 °C), which has a similar viscosity to the synovial fluid in a joint with inflammatory disease (Figure S4, Supporting Information).…”

Section: Resultsmentioning

confidence: 99%

A Magnetically Actuated Microscaffold Containing Mesenchymal Stem Cells for Articular Cartilage Repair

Han

Jin

et al. 2017

Adv Healthcare Materials

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This study proposes a magnetically actuated microscaffold with the capability of targeted mesenchymal stem cell (MSC) delivery for articular cartilage regeneration. The microscaffold, as a 3D porous microbead, is divided into body and surface portions according to its materials and fabrication methods. The microscaffold body, which consists of poly(lactic-co-glycolic acid) (PLGA), is formed through water-in-oil-in-water emulsion templating, and its surface is coated with amine functionalized magnetic nanoparticles (MNPs) via amino bond formation. The porous PLGA structure of the microscaffold can assist in cell adhesion and migration, and the MNPs on the microscaffold can make it possible to steer using an electromagnetic actuation system that provides external magnetic fields for the 3D locomotion of the microscaffold. As a fundamental test of the magnetic response of the microscaffold, it is characterized in terms of the magnetization curve, velocity, and 3D locomotion of a single microscaffold. In addition, its function with a cargo of MSCs for cartilage regeneration is demonstrated from the proliferation, viability, and chondrogenic differentiation of D1 mouse MSCs that are cultured on the microscaffold. For the feasibility tests for cartilage repair, 2D/3D targeting of multiple microscaffolds with the MSCs is performed to demonstrate targeted stem cell delivery using the microscaffolds and their swarm motion.

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“…The measured outcomes such as friction, wear, wear debris, and film thickness provide clear evidence of the tribological mechanism. Despite good performance of artificial joints in vitro , they are often found to fail in vivo after 10–15 years of implantation [14]. To understand this better, some research has emphasized the effect of biological components of synovial fluid on the implanted joints.…”

Section: Introductionmentioning

confidence: 99%

Tribological performance of the biological components of synovial fluid in artificial joint implants

Ghosh

Choudhury

Roy

et al. 2015

Science and Technology of Advanced Materials

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The concentration of biological components of synovial fluid (such as albumin, globulin, hyaluronic acid, and lubricin) varies between healthy persons and osteoarthritis (OA) patients. The aim of the present study is to compare the effects of such variation on tribological performance in a simulated hip joint model. The study was carried out experimentally by utilizing a pin-on-disk simulator on ceramic-on-ceramic (CoC) and ceramic-on-polyethylene (CoP) hip joint implants. The experimental results show that both friction and wear of artificial joints fluctuate with the concentration level of biological components. Moreover, the performance also varies between material combinations. Wear debris sizes and shapes produced by ceramic and polyethylene were diverse. We conclude that the biological components of synovial fluid and their concentrations should be considered in order to select an artificial hip joint to best suit that patient.

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Performance of honed surface profiles to artificial hip joints: An experimental investigation

Cited by 35 publications

References 18 publications

Tribological investigation of diamond-like carbon coated micro-dimpled surface under bovine serum and osteoarthritis oriented synovial fluid

Tribological investigation of diamond-like carbon coated micro-dimpled surface under bovine serum and osteoarthritis oriented synovial fluid

A Magnetically Actuated Microscaffold Containing Mesenchymal Stem Cells for Articular Cartilage Repair

Tribological performance of the biological components of synovial fluid in artificial joint implants

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